| Sep 23, 2004 | La Salle 30, St. Peter’s 27 | Box score |
| Sep 25, 2004 | New Hampshire 45, Dartmouth 24 | Box score |
| Sep 25, 2004 | Harvard 35, Brown 34 | Box score |
| Sep 25, 2004 | Howard 53, Savannah State 7 | Box score |
| Sep 25, 2004 | Delaware 21, Massachusetts 7 | Box score |
| Sep 25, 2004 | Cornell 19, Yale 7 | Box score |
| Sep 25, 2004 | Pittsburgh 41, Furman 38 | Box score |
| Sep 25, 2004 | Lafayette 21, Richmond 16 | Box score |
| Sep 25, 2004 | Bethune-Cookman 43, Norfolk State 3 | Box score |
| Sep 25, 2004 | Colgate 33, Georgetown 0 | Box score |
| Sep 25, 2004 | Southern Illinois 49, Delaware State 0 | Box score |
| Sep 25, 2004 | Fordham 41, Duquesne 34 | Box score |
| Sep 25, 2004 | Stony Brook 27, Monmouth 0upset | Box score |
| Sep 25, 2004 | UAlbany 23, Sacred Heart 6 | Box score |
| Sep 25, 2004 | Robert Morris 28, Saint Francis 10 | Box score |
| Sep 25, 2004 | William & Mary 42, VMI 6 | Box score |
| Sep 25, 2004 | Charleston Southern 38, Charleston (WV) 21 | Box score |
| Sep 25, 2004 | North Carolina A&T 19, Elon 17 | Box score |
| Sep 25, 2004 | Indiana State 41, UT Martin 24 | Box score |
| Sep 25, 2004 | 9Auburn 33, The Citadel 3 | Box score |
| Sep 25, 2004 | Colorado State 39, Montana State 14 | Box score |
| Sep 25, 2004 | Florida A&M 21, Tennessee State 15upset | Box score |
| Sep 25, 2004 | Montana 27, Northern Colorado 16 | Box score |
| Sep 25, 2004 | Hofstra 62, Rhode Island 43 | Box score |
| Sep 25, 2004 | Georgia Southern 51, Chattanooga 17 | Box score |
| Sep 25, 2004 | 6West Virginia 45, James Madison 10 | Box score |
| Sep 25, 2004 | Princeton 24, San Diego 17 | Box score |
| Sep 25, 2004 | Hampton 49, Morgan State 37 | Box score |
| Sep 25, 2004 | Northwestern State 40, App State 35 | Box score |
| Sep 25, 2004 | Northeastern 27, Towson 3 | Box score |
| Sep 25, 2004 | Central Connecticut 28, Wagner 21 | Box score |
| Sep 25, 2004 | Eastern Illinois 31, Eastern Michigan 28upset | Box score |
| Sep 25, 2004 | Gardner-Webb 26, Western Carolina 20 | Box score |
| Sep 25, 2004 | Youngstown State 27, Liberty 17 | Box score |
| Sep 25, 2004 | UC Davis 58, Sacramento State 23 | Box score |
| Sep 25, 2004 | Jacksonville State 30, Eastern Kentucky 23 | Box score |
| Sep 25, 2004 | Murray State 34, Tennessee Tech 15 | Box score |
| Sep 25, 2004 | Tulsa 49, Missouri State 7 | Box score |
| Sep 25, 2004 | Villanova 16, Pennsylvania 13upset | Box score |
| Sep 25, 2004 | Coastal Carolina 58, North Greenville 7 | Box score |
| Sep 25, 2004 | Bucknell 42, Columbia 13 | Box score |
| Sep 25, 2004 | Marist 41, Iona 14 | Box score |
| Sep 25, 2004 | Sam Houston 45, SE Louisiana 17upset | Box score |
| Sep 25, 2004 | Southeast Missouri State 51, Samford 48 | Box score |
| Sep 25, 2004 | Wofford 56, Johnson C. Smith 0 | Box score |
| Sep 25, 2004 | Western Illinois 38, Quincy 31 | Box score |
| Sep 25, 2004 | Stephen F. Austin 24, Southern Utah 21 | Box score |
| Sep 25, 2004 | Nicholls 21, Texas Southern 6 | Box score |
| Sep 25, 2004 | Eastern Washington 47, Idaho State 22 | Box score |
| Sep 25, 2004 | Northern Arizona 55, Weber State 27 | Box score |
| Sep 25, 2004 | Portland State 35, McNeese 14 | Box score |