| Sep 16, 2004 | Central Connecticut 30, St. Peter’s 15 | Box score |
| Sep 18, 2004 | William & Mary 9, New Hampshire 7 | Box score |
| Sep 18, 2004 | Charleston Southern 38, Jacksonville 3upset | Box score |
| Sep 18, 2004 | Harvard 35, Holy Cross 0 | Box score |
| Sep 18, 2004 | Richmond 24, Massachusetts 14upset | Box score |
| Sep 18, 2004 | James Madison 17, Villanova 0 | Box score |
| Sep 18, 2004 | Brown 35, UAlbany 7 | Box score |
| Sep 18, 2004 | Central Michigan 44, Southeast Missouri State 27 | Box score |
| Sep 18, 2004 | Colgate 17, Dartmouth 15 | Box score |
| Sep 18, 2004 | Yale 24, Dayton 17 | Box score |
| Sep 18, 2004 | The College of New Jersey 6, La Salle 0 | Box score |
| Sep 18, 2004 | Saint Francis 17, Valparaiso 13 | Box score |
| Sep 18, 2004 | Tennessee Tech 16, VMI 10 | Box score |
| Sep 18, 2004 | Wagner 21, Stony Brook 13 | Box score |
| Sep 18, 2004 | Grambling 24, Bethune-Cookman 23 | Box score |
| Sep 18, 2004 | Duquesne 45, Georgetown 7 | Box score |
| Sep 18, 2004 | Hampton 40, Western Illinois 20 | Box score |
| Sep 18, 2004 | Monmouth 29, Robert Morris 27 | Box score |
| Sep 18, 2004 | Indiana State 28, Murray State 21 | Box score |
| Sep 18, 2004 | App State 28, The Citadel 14 | Box score |
| Sep 18, 2004 | Elon 49, Delaware State 13 | Box score |
| Sep 18, 2004 | Idaho State 49, Northern Colorado 42 | Box score |
| Sep 18, 2004 | Sacred Heart 48, Iona 7 | Box score |
| Sep 18, 2004 | Cal Poly 27, Montana State 14 | Box score |
| Sep 18, 2004 | South Carolina State 55, Savannah State 20 | Box score |
| Sep 18, 2004 | Howard 17, Alcorn State 10 | Box score |
| Sep 18, 2004 | Pennsylvania 61, San Diego 18 | Box score |
| Sep 18, 2004 | San José State 47, Morgan State 28 | Box score |
| Sep 18, 2004 | Stephen F. Austin 24, Northern Iowa 21 | Box score |
| Sep 18, 2004 | Jacksonville State 65, Chattanooga 20 | Box score |
| Sep 18, 2004 | Furman 38, Gardner-Webb 6 | Box score |
| Sep 18, 2004 | Wake Forest 42, North Carolina A&T 3 | Box score |
| Sep 18, 2004 | Delaware 24, West Chester 6 | Box score |
| Sep 18, 2004 | Southern Illinois 59, William Penn 9 | Box score |
| Sep 18, 2004 | Princeton 35, Lafayette 18upset | Box score |
| Sep 18, 2004 | Fordham 17, Columbia 14 | Box score |
| Sep 18, 2004 | Texas State 31, SE Louisiana 28 | Box score |
| Sep 18, 2004 | Alabama 52, Western Carolina 0 | Box score |
| Sep 18, 2004 | Maine 9, Mississippi State 7upset | Box score |
| Sep 18, 2004 | UT Martin 31, Austin Peay 14upset | Box score |
| Sep 18, 2004 | Bucknell 15, Cornell 9 | Box score |
| Sep 18, 2004 | Lehigh 34, Liberty 16 | Box score |
| Sep 18, 2004 | Newberry 21, Coastal Carolina 7upset | Box score |
| Sep 18, 2004 | Northwestern State 52, Texas Southern 6 | Box score |
| Sep 18, 2004 | Missouri State 45, Union College 0 | Box score |
| Sep 18, 2004 | Tennessee State 21, Jackson State 20 | Box score |
| Sep 18, 2004 | Georgia Southern 58, Wofford 14 | Box score |
| Sep 18, 2004 | Western Kentucky 21, Eastern Kentucky 8 | Box score |
| Sep 18, 2004 | Illinois State 35, Eastern Illinois 31 | Box score |
| Sep 18, 2004 | UC Davis 31, Weber State 29 | Box score |
| Sep 18, 2004 | McNeese 24, Youngstown State 20 | Box score |
| Sep 18, 2004 | Sam Houston 41, Montana 29upset | Box score |
| Sep 18, 2004 | Eastern Washington 39, Central Washington 8 | Box score |
| Sep 18, 2004 | 19Fresno State 27, Portland State 17 | Box score |
| Sep 18, 2004 | Sacramento State 23, Southern Utah 17 | Box score |