| Sep 2, 2004 | New Hampshire 24, Delaware 21 | Box score |
| Sep 2, 2004 | Villanova 20, Bucknell 14 | Box score |
| Sep 2, 2004 | Hofstra 45, UAlbany 0upset | Box score |
| Sep 2, 2004 | Missouri State 31, Drake 26 | Box score |
| Sep 2, 2004 | Western Carolina 77, West Virginia State 7 | Box score |
| Sep 2, 2004 | Nicholls 37, Eastern Washington 14 | Box score |
| Sep 2, 2004 | Youngstown State 35, Slippery Rock 13 | Box score |
| Sep 2, 2004 | Southern Illinois 42, Southeast Missouri State 3 | Box score |
| Sep 2, 2004 | Illinois State 44, Saint Xavier 14 | Box score |
| Sep 2, 2004 | SE Louisiana 46, Arkansas Monticello 32 | Box score |
| Sep 2, 2004 | Stephen F. Austin 30, Henderson State 14 | Box score |
| Sep 2, 2004 | Western Michigan 42, UT Martin 0 | Box score |
| Sep 2, 2004 | Portland State 38, Western Colorado 0 | Box score |
| Sep 4, 2004 | UConn 52, Murray State 14 | Box score |
| Sep 4, 2004 | Duquesne 31, Holy Cross 7 | Box score |
| Sep 4, 2004 | Georgetown 36, Saint Francis 7 | Box score |
| Sep 4, 2004 | Georgia Tech 28, Samford 7 | Box score |
| Sep 4, 2004 | Montclair State 42, Iona 27 | Box score |
| Sep 4, 2004 | Lafayette 48, Marist 7 | Box score |
| Sep 4, 2004 | Alabama State 27, Howard 12 | Box score |
| Sep 4, 2004 | Massachusetts 51, Delaware State 0 | Box score |
| Sep 4, 2004 | Rhode Island 37, Fordham 36upset | Box score |
| Sep 4, 2004 | Wagner 35, La Salle 28 | Box score |
| Sep 4, 2004 | Lehigh 25, Stony Brook 2 | Box score |
| Sep 4, 2004 | Central Connecticut 27, Sacred Heart 6 | Box score |
| Sep 4, 2004 | Robert Morris 47, Buffalo State 10 | Box score |
| Sep 4, 2004 | North Carolina 49, William & Mary 38 | Box score |
| Sep 4, 2004 | Iowa State 23, Northern Iowa 0 | Box score |
| Sep 4, 2004 | Northeastern 71, Cheyney 0 | Box score |
| Sep 4, 2004 | Towson 34, Elon 13 | Box score |
| Sep 4, 2004 | Jacksonville State 25, Emporia State 16 | Box score |
| Sep 4, 2004 | Georgia 48, Georgia Southern 28 | Box score |
| Sep 4, 2004 | Wyoming 53, App State 7 | Box score |
| Sep 4, 2004 | Montana 27, Maine 20 | Box score |
| Sep 4, 2004 | Northern Colorado 15, North Dakota State 13 | Box score |
| Sep 4, 2004 | NC State 42, Richmond 0 | Box score |
| Sep 4, 2004 | James Madison 62, Lock Haven 7 | Box score |
| Sep 4, 2004 | Morgan State 41, Bowie State 35 | Box score |
| Sep 4, 2004 | Virginia State 17, Norfolk State 7 | Box score |
| Sep 4, 2004 | South Carolina State 51, Benedict 0 | Box score |
| Sep 4, 2004 | Nebraska 56, Western Illinois 17 | Box score |
| Sep 4, 2004 | Ohio 42, VMI 14 | Box score |
| Sep 4, 2004 | Furman 52, Presbyterian 7 | Box score |
| Sep 4, 2004 | Texas State 45, Angelo State 10 | Box score |
| Sep 4, 2004 | Hampton 38, Jackson State 19 | Box score |
| Sep 4, 2004 | Liberty 55, WVU Tech 17 | Box score |
| Sep 4, 2004 | Coastal Carolina 28, Morehead State 7 | Box score |
| Sep 4, 2004 | Sam Houston 60, Ouachita Baptist 7 | Box score |
| Sep 4, 2004 | Monmouth 44, St. Peter’s 3 | Box score |
| Sep 4, 2004 | Kansas State 27, Western Kentucky 13 | Box score |
| Sep 4, 2004 | Tennessee State 42, Alabama A&M 7 | Box score |
| Sep 4, 2004 | Louisiana 14, Northwestern State 7 | Box score |
| Sep 4, 2004 | McNeese 35, Southern 17 | Box score |
| Sep 4, 2004 | Tennessee Tech 32, Gardner-Webb 26 | Box score |
| Sep 4, 2004 | Cal Poly 42, Humboldt State 7 | Box score |
| Sep 4, 2004 | San Diego State 38, Idaho State 21 | Box score |
| Sep 4, 2004 | Southern Utah 34, Weber State 31 | Box score |
| Sep 4, 2004 | Arizona 21, Northern Arizona 3 | Box score |
| Sep 5, 2004 | North Carolina A&T 16, North Carolina Central 15 | Box score |
