1921: Week 7
53 games. Winners are listed first; numbers before names are AP ranks going in.
FBS vs. FBS
| Oct 27, 1921 | South Carolina 21, Clemson 0 | Box score |
| Oct 29, 1921 | Alabama 7, LSU 7 | Box score |
| Oct 29, 1921 | Arkansas 14, SMU 0 | Box score |
| Oct 29, 1921 | Baylor 16, Southwestern U 0 | Box score |
| Oct 29, 1921 | California 14, Washington State 0 | Box score |
| Oct 29, 1921 | Centre 6, Harvard 0 | Box score |
| Oct 29, 1921 | Chicago 35, Colorado 0 | Box score |
| Oct 29, 1921 | Colorado State 24, Colorado College 0 | Box score |
| Oct 29, 1921 | Cornell 59, Dartmouth 7 | Box score |
| Oct 29, 1921 | Richmond 14, Davidson 14 | Box score |
| Oct 29, 1921 | Furman 42, The Citadel 0 | Box score |
| Oct 29, 1921 | Georgia 7, Auburn 0 | Box score |
| Oct 29, 1921 | Iowa 13, Purdue 6 | Box score |
| Oct 29, 1921 | Kansas 21, Kansas State 7 | Box score |
| Oct 29, 1921 | Lafayette 35, Rutgers 0 | Box score |
| Oct 29, 1921 | Michigan 3, Illinois 0 | Box score |
| Oct 29, 1921 | Mississippi College 27, Birmingham-Southern 6 | Box score |
| Oct 29, 1921 | Mississippi State 21, Ole Miss 0 | Box score |
| Oct 29, 1921 | Missouri 6, Drake 0 | Box score |
| Oct 29, 1921 | Nebraska 44, Oklahoma 0 | Box score |
| Oct 29, 1921 | North Carolina 16, Maryland 7upset | Box score |
| Oct 29, 1921 | Notre Dame 28, Indiana 7 | Box score |
| Oct 29, 1921 | Oglethorpe 7, Chattanooga 0 | Box score |
| Oct 29, 1921 | Penn State 28, Georgia Tech 7 | Box score |
| Oct 29, 1921 | Pittsburgh 28, Pennsylvania 0 | Box score |
| Oct 29, 1921 | Princeton 34, Virginia 0 | Box score |
| Oct 29, 1921 | Sewanee 6, Kentucky 0 | Box score |
| Oct 29, 1921 | Stanford 14, Oregon State 7 | Box score |
| Oct 29, 1921 | Texas 56, Rice 0 | Box score |
| Oct 29, 1921 | Texas A&M 23, Oklahoma State 7 | Box score |
| Oct 29, 1921 | Phillips 0, TCU 0 | Box score |
| Oct 29, 1921 | Utah 17, Idaho 7 | Box score |
| Oct 29, 1921 | Vanderbilt 14, Tennessee 0 | Box score |
| Oct 29, 1921 | NC State 7, VMI 7 | Box score |
| Oct 29, 1921 | Washington & Jefferson 17, Syracuse 10 | Box score |
| Oct 29, 1921 | Washington and Lee 3, Virginia Tech 0 | Box score |
| Oct 29, 1921 | Washington St. Louis 2, Iowa State 0 | Box score |
| Oct 29, 1921 | Wisconsin 35, Minnesota 0 | Box score |
| Oct 29, 1921 | Denver 9, Wyoming 9 | Box score |
| Oct 29, 1921 | Yale 45, Brown 7 | Box score |
Everyone else
| Oct 29, 1921 | Detroit Mercy 14, Tulane 10upset | Box score |
| Oct 29, 1921 | Erskine 19, Presbyterian 7 | Box score |
| Oct 29, 1921 | Florida 34, Samford 0 | Box score |
| Oct 29, 1921 | Lehigh 21, West Virginia 12upset | Box score |
| Oct 29, 1921 | Mercer 41, Stetson 0 | Box score |
| Oct 29, 1921 | Navy 21, Bethany (WV) 0 | Box score |
| Oct 29, 1921 | New York University 7, Colgate 7 | Box score |
| Oct 29, 1921 | Newberry 33, Wofford 21 | Box score |
| Oct 29, 1921 | Northwestern 34, DePaul 0 | Box score |
| Oct 29, 1921 | Spring Hill 41, Marion 0 | Box score |
| Oct 29, 1921 | Utah State 3, Montana Tech 0 | Box score |
| Oct 29, 1921 | Wake Forest 28, Guilford 0 | Box score |
| Oct 29, 1921 | Williams 20, Columbia 0upset | Box score |