| Oct 3, 1905 | Alabama 17, Maryville (TN) 0 | Box score |
| Oct 4, 1905 | Bates 28, Colby 0 | Box score |
| Oct 4, 1905 | Carlisle 47, Susquehanna 0 | Box score |
| Oct 4, 1905 | Columbia 21, Seton Hall 0 | Box score |
| Oct 4, 1905 | Cornell 28, Hobart 0 | Box score |
| Oct 4, 1905 | Kansas 45, Emporia College 0 | Box score |
| Oct 4, 1905 | Lehigh 23, Medico-Chirurgical 0 | Box score |
| Oct 4, 1905 | Michigan 44, Kalamazoo 0 | Box score |
| Oct 4, 1905 | Pennsylvania 16, Gettysburg 6 | Box score |
| Oct 4, 1905 | Wisconsin 29, Marquette 0 | Box score |
| Oct 6, 1905 | Haskell 12, Fort Hays 0 | Box score |
| Oct 6, 1905 | Missouri 26, Simpson (IA) 0 | Box score |
| Oct 7, 1905 | Bates 16, Massachusetts 0 | Box score |
| Oct 7, 1905 | Brown 70, Colby 0 | Box score |
| Oct 7, 1905 | Colorado 109, Regis (CO) 0 | Box score |
| Oct 7, 1905 | Colorado College 36, North Denver High 0 | Box score |
| Oct 7, 1905 | Dickinson 44, Haverford 0 | Box score |
| Oct 7, 1905 | Exeter 11, Bowdoin 0 | Box score |
| Oct 7, 1905 | Georgia Tech 54, North Georgia 0 | Box score |
| Oct 7, 1905 | Grinnell 6, William Penn 5 | Box score |
| Oct 7, 1905 | Harvard 22, Maine 0 | Box score |
| Oct 7, 1905 | Illinois 24, North Central College 0 | Box score |
| Oct 7, 1905 | Iowa State 28, Northern Iowa 0 | Box score |
| Oct 7, 1905 | Knox 47, Illinois Wesleyan 0 | Box score |
| Oct 7, 1905 | Lafayette 18, Ursinus 0 | Box score |
| Oct 7, 1905 | Lehigh 11, New York University 2 | Box score |
| Oct 7, 1905 | Michigan 36, Case 0 | Box score |
| Oct 7, 1905 | Minnesota 45, North Dakota 0 | Box score |
| Oct 7, 1905 | Nebraska 42, South Dakota 6 | Box score |
| Oct 7, 1905 | Notre Dame 28, Michigan State 0 | Box score |
| Oct 7, 1905 | Pittsburgh 57, Mount Union 0 | Box score |
| Oct 7, 1905 | Steelton YMCA 6, Villanova 0 | Box score |
| Oct 7, 1905 | Tennessee 104, American 0 | Box score |
| Oct 7, 1905 | Tufts 13, New Hampshire 0 | Box score |
| Oct 7, 1905 | Vermont 11, Middlebury 0 | Box score |
| Oct 7, 1905 | Washburn 29, Emporia State 6 | Box score |
| Oct 7, 1905 | Washington & Jefferson 57, Ohio 0 | Box score |
| Oct 7, 1905 | Washington St. Louis 0, Rose Hulman 0 | Box score |
| Oct 7, 1905 | Williams 12, Union (NY) 0 | Box score |
| Oct 9, 1905 | Kansas 11, Drury 0 | Box score |
| Oct 9, 1905 | Oklahoma 28, Central Oklahoma 0 | Box score |