| Oct 8, 2009 | Colgate 21, Princeton 14 | Box score |
| Oct 10, 2009 | Yale 38, Dartmouth 7 | Box score |
| Oct 10, 2009 | New Hampshire 28, Villanova 24 | Box score |
| Oct 10, 2009 | 14Penn State 52, Eastern Illinois 3 | Box score |
| Oct 10, 2009 | Richmond 21, James Madison 17 | Box score |
| Oct 10, 2009 | Central Connecticut 42, Robert Morris 21 | Box score |
| Oct 10, 2009 | Sacred Heart 29, Saint Francis 7 | Box score |
| Oct 10, 2009 | Harvard 28, Cornell 10 | Box score |
| Oct 10, 2009 | Brown 34, Holy Cross 31 | Box score |
| Oct 10, 2009 | Lehigh 27, Georgetown 0 | Box score |
| Oct 10, 2009 | William & Mary 34, Northeastern 14 | Box score |
| Oct 10, 2009 | Pennsylvania 21, Bucknell 3 | Box score |
| Oct 10, 2009 | Towson 36, Rhode Island 28 | Box score |
| Oct 10, 2009 | UAlbany 55, Duquesne 10 | Box score |
| Oct 10, 2009 | Dayton 35, Campbell 17 | Box score |
| Oct 10, 2009 | Davidson 16, Morehead State 10 | Box score |
| Oct 10, 2009 | Maine 16, Hofstra 14 | Box score |
| Oct 10, 2009 | Marist 31, Jacksonville 27 | Box score |
| Oct 10, 2009 | Wagner 27, Monmouth 24upset | Box score |
| Oct 10, 2009 | Morgan State 7, North Carolina A&T 6 | Box score |
| Oct 10, 2009 | South Carolina State 37, Norfolk State 10 | Box score |
| Oct 10, 2009 | Elon 43, The Citadel 7 | Box score |
| Oct 10, 2009 | North Dakota 31, Stony Brook 24 | Box score |
| Oct 10, 2009 | Prairie View A&M 24, Alabama State 10 | Box score |
| Oct 10, 2009 | Drake 19, Missouri S&T 0 | Box score |
| Oct 10, 2009 | Austin Peay 24, Southeast Missouri State 14 | Box score |
| Oct 10, 2009 | San Diego 48, Valparaiso 7 | Box score |
| Oct 10, 2009 | Southern Illinois 43, Illinois State 23 | Box score |
| Oct 10, 2009 | UC Davis 24, South Dakota 23 | Box score |
| Oct 10, 2009 | SE Louisiana 51, Texas State 50 | Box score |
| Oct 10, 2009 | Sam Houston 44, Nicholls 21 | Box score |
| Oct 10, 2009 | South Dakota State 24, Missouri State 17 | Box score |
| Oct 10, 2009 | Tennessee Tech 35, UT Martin 28upset | Box score |
| Oct 10, 2009 | Montana 35, Cal Poly 23 | Box score |
| Oct 10, 2009 | North Carolina 42, Georgia Southern 12 | Box score |
| Oct 10, 2009 | Rutgers 42, Texas Southern 0 | Box score |
| Oct 10, 2009 | App State 55, North Carolina Central 21 | Box score |
| Oct 10, 2009 | Buffalo 40, Gardner-Webb 3 | Box score |
| Oct 10, 2009 | Northern Arizona 23, Montana State 10upset | Box score |
| Oct 10, 2009 | Weber State 31, Eastern Washington 13 | Box score |
| Oct 10, 2009 | Portland State 23, Northern Colorado 18 | Box score |
| Oct 10, 2009 | Jacksonville State 41, Murray State 7 | Box score |
| Oct 10, 2009 | Chattanooga 14, Samford 7upset | Box score |
| Oct 10, 2009 | Grambling 41, Alabama A&M 20 | Box score |
| Oct 10, 2009 | Northern Iowa 42, North Dakota State 27 | Box score |
| Oct 10, 2009 | Alcorn State 32, Mississippi Valley State 10 | Box score |
| Oct 10, 2009 | Arkansas–Pine Bluff 20, Jackson State 13upset | Box score |
| Oct 10, 2009 | Sacramento State 38, Idaho State 17 | Box score |
| Oct 10, 2009 | Delaware 43, Massachusetts 27 | Box score |
| Oct 10, 2009 | Old Dominion 34, Presbyterian 16 | Box score |
| Oct 10, 2009 | Lafayette 24, Columbia 21 | Box score |
| Oct 10, 2009 | Tennessee State 20, Eastern Kentucky 17upset | Box score |
| Oct 10, 2009 | Fordham 35, Bryant 7 | Box score |
| Oct 10, 2009 | Hampton 37, Howard 0 | Box score |
| Oct 10, 2009 | Youngstown State 31, Western Illinois 21 | Box score |
| Oct 10, 2009 | Coastal Carolina 20, VMI 6 | Box score |
| Oct 10, 2009 | Bethune-Cookman 9, Delaware State 7upset | Box score |
| Oct 10, 2009 | 11Miami 48, Florida A&M 16 | Box score |
| Oct 10, 2009 | Stephen F. Austin 16, McNeese 13 | Box score |
| Oct 10, 2009 | Central Arkansas 34, Northwestern State 0 | Box score |