1961: Week 2
44 games. Winners are listed first; numbers before names are AP ranks going in.
FBS vs. FBS
| Sep 22, 1961 | Detroit Mercy 21, Western Michigan 14 | Box score |
| Sep 22, 1961 | Georgia Tech 27, USC 7 | Box score |
| Sep 22, 1961 | San José State 16, Pacific 0 | Box score |
| Sep 23, 1961 | Alabama 32, Georgia 6 | Box score |
| Sep 23, 1961 | Arizona 28, Colorado State 6 | Box score |
| Sep 23, 1961 | Arizona State 21, Wichita State 7 | Box score |
| Sep 23, 1961 | Army 24, Richmond 6 | Box score |
| Sep 23, 1961 | Baylor 31, Wake Forest 0 | Box score |
| Sep 23, 1961 | Boston College 23, Cincinnati 0 | Box score |
| Sep 23, 1961 | Buffalo 24, Boston University 12upset | Box score |
| Sep 23, 1961 | Duke 7, South Carolina 6 | Box score |
| Sep 23, 1961 | Florida 21, Clemson 17 | Box score |
| Sep 23, 1961 | George Washington 17, The Citadel 13 | Box score |
| Sep 23, 1961 | Texas A&M 7, Houston 7 | Box score |
| Sep 23, 1961 | Iowa State 14, Oklahoma State 7 | Box score |
| Sep 23, 1961 | Kansas State 14, Indiana 8 | Box score |
| Sep 23, 1961 | Kent State 38, Dayton 14 | Box score |
| Sep 23, 1961 | Maryland 14, SMU 6 | Box score |
| Sep 23, 1961 | Memphis 48, Tulsa 12 | Box score |
| Sep 23, 1961 | Miami 14, Kentucky 7 | Box score |
| Sep 23, 1961 | Miami (OH) 3, Xavier 0 | Box score |
| Sep 23, 1961 | Ole Miss 16, Arkansas 0 | Box score |
| Sep 23, 1961 | Mississippi State 6, Texas Tech 0 | Box score |
| Sep 23, 1961 | Missouri 28, Washington State 6 | Box score |
| Sep 23, 1961 | New Mexico 41, New Mexico State 7 | Box score |
| Sep 23, 1961 | North Texas 9, Hardin Simmons 7 | Box score |
| Sep 23, 1961 | Oregon 51, Idaho 0 | Box score |
| Sep 23, 1961 | Penn State 20, Navy 10 | Box score |
| Sep 23, 1961 | Purdue 13, Washington 6upset | Box score |
| Sep 23, 1961 | Rice 16, LSU 3 | Box score |
| Sep 23, 1961 | Stanford 9, Tulane 7 | Box score |
| Sep 23, 1961 | Syracuse 19, Oregon State 8 | Box score |
| Sep 23, 1961 | Texas 28, California 3 | Box score |
| Sep 23, 1961 | TCU 17, Kansas 16 | Box score |
| Sep 23, 1961 | UCLA 19, Air Force 6 | Box score |
| Sep 23, 1961 | Utah State 54, Montana 6 | Box score |
| Sep 23, 1961 | Vanderbilt 16, West Virginia 6 | Box score |
| Sep 23, 1961 | Villanova 22, VMI 0 | Box score |
| Sep 23, 1961 | Virginia 21, William & Mary 6 | Box score |
| Sep 23, 1961 | West Texas 55, BYU 8 | Box score |
| Sep 23, 1961 | Wisconsin 7, Utah 0 | Box score |
| Sep 23, 1961 | Wyoming 15, NC State 14 | Box score |