1961: Week 1
20 games. Winners are listed first; numbers before names are AP ranks going in.
FBS vs. FBS
| Sep 16, 1961 | Cincinnati 16, Dayton 12 | Box score |
| Sep 16, 1961 | Florida State 15, George Washington 7 | Box score |
| Sep 16, 1961 | Iowa State 21, Drake 0 | Box score |
| Sep 16, 1961 | Memphis 40, The Citadel 0 | Box score |
| Sep 16, 1961 | Pittsburgh 10, Miami 7 | Box score |
| Sep 16, 1961 | Richmond 35, West Virginia 26 | Box score |
| Sep 16, 1961 | San José State 14, BYU 13 | Box score |
| Sep 16, 1961 | Tulsa 27, Hardin Simmons 0 | Box score |
| Sep 16, 1961 | Utah 40, Colorado State 0 | Box score |
| Sep 16, 1961 | Utah State 21, UTEP 6 | Box score |
| Sep 16, 1961 | Villanova 33, Miami (OH) 0upset | Box score |
| Sep 16, 1961 | VMI 33, Marshall 6 | Box score |
| Sep 16, 1961 | Virginia Tech 20, William & Mary 6 | Box score |
| Sep 16, 1961 | Wichita State 12, Toledo 7 | Box score |
| Sep 16, 1961 | Wyoming 29, Montana 0 | Box score |
| Sep 16, 1961 | Xavier 16, Kent State 8 | Box score |