| Oct 24, 1946 | South Carolina 26, Clemson 14 | Box score |
| Oct 25, 1946 | Boston College 14, Villanova 12 | Box score |
| Oct 25, 1946 | Detroit Mercy 33, Drake 6 | Box score |
| Oct 25, 1946 | Miami 33, Chattanooga 13 | Box score |
| Oct 26, 1946 | 11Alabama 21, Kentucky 7 | Box score |
| Oct 26, 1946 | 1Army 19, 13Duke 0 | Box score |
| Oct 26, 1946 | Bucknell 29, Lafayette 0 | Box score |
| Oct 26, 1946 | Cincinnati 18, Michigan State 7upset | Box score |
| Oct 26, 1946 | Colorado 14, New Mexico 13 | Box score |
| Oct 26, 1946 | Columbia 33, Dartmouth 13 | Box score |
| Oct 26, 1946 | Cornell 14, Princeton 7upset | Box score |
| Oct 26, 1946 | Georgetown 13, Saint Louis 7 | Box score |
| Oct 26, 1946 | 7Georgia 70, Furman 7 | Box score |
| Oct 26, 1946 | 15Georgia Tech 27, Auburn 6 | Box score |
| Oct 26, 1946 | Hardin Simmons 46, Arizona State 6 | Box score |
| Oct 26, 1946 | 20Harvard 13, Holy Cross 6 | Box score |
| Oct 26, 1946 | Illinois 13, 8Michigan 9upset | Box score |
| Oct 26, 1946 | Indiana 27, Nebraska 7 | Box score |
| Oct 26, 1946 | LSU 14, Vanderbilt 0 | Box score |
| Oct 26, 1946 | Marquette 20, Arizona 0 | Box score |
| Oct 26, 1946 | Merchant Marine 7, Fordham 6 | Box score |
| Oct 26, 1946 | Ole Miss 9, Arkansas 7 | Box score |
| Oct 26, 1946 | Mississippi State 14, Tulane 7 | Box score |
| Oct 26, 1946 | Montana State 27, Northern Colorado 7 | Box score |
| Oct 26, 1946 | 10North Carolina 40, Florida 19 | Box score |
| Oct 26, 1946 | 2Notre Dame 41, 17Iowa 6 | Box score |
| Oct 26, 1946 | Ohio State 39, Minnesota 9 | Box score |
| Oct 26, 1946 | 14Oklahoma 63, Iowa State 0 | Box score |
| Oct 26, 1946 | Oklahoma State 7, TCU 6 | Box score |
| Oct 26, 1946 | 19Oregon 26, Idaho 13 | Box score |
| Oct 26, 1946 | Oregon State 13, Washington State 12 | Box score |
| Oct 26, 1946 | Penn State 6, Colgate 2 | Box score |
| Oct 26, 1946 | 6Pennsylvania 32, Navy 19 | Box score |
| Oct 26, 1946 | Purdue 10, Pittsburgh 8 | Box score |
| Oct 26, 1946 | 16Rice 18, 3Texas 13upset | Box score |
| Oct 26, 1946 | Richmond 20, Washington and Lee 0upset | Box score |
| Oct 26, 1946 | Rutgers 25, George Washington 13upset | Box score |
| Oct 26, 1946 | USC 28, Stanford 20upset | Box score |
| Oct 26, 1946 | SMU 17, Missouri 0upset | Box score |
| Oct 26, 1946 | Texas A&M 17, Baylor 0 | Box score |
| Oct 26, 1946 | Texas Tech 21, Denver 6 | Box score |
| Oct 26, 1946 | Tulsa 56, Kansas 0 | Box score |
| Oct 26, 1946 | 5UCLA 33, Santa Clara 7 | Box score |
| Oct 26, 1946 | Utah 27, Wyoming 7 | Box score |
| Oct 26, 1946 | Utah State 26, Montana 0 | Box score |
| Oct 26, 1946 | Virginia Tech 14, 12NC State 6upset | Box score |
| Oct 26, 1946 | Wake Forest 19, 4Tennessee 6upset | Box score |
| Oct 26, 1946 | Washington 20, California 6 | Box score |
| Oct 26, 1946 | West Texas 21, New Mexico State 14 | Box score |
| Oct 26, 1946 | West Virginia 13, Syracuse 0 | Box score |
| Oct 26, 1946 | 18William & Mary 41, VMI 0 | Box score |
| Oct 27, 1946 | Saint Mary’s (CA) 13, Nevada 12 | Box score |