| Oct 18, 1940 | Detroit Mercy 6, Manhattan 0 | Box score |
| Oct 18, 1940 | Temple 21, Michigan State 19 | Box score |
| Oct 18, 1940 | Texas Tech 21, BYU 20 | Box score |
| Oct 18, 1940 | Tulsa 19, Saint Louis 6 | Box score |
| Oct 19, 1940 | Arizona 29, Centenary (LA) 6 | Box score |
| Oct 19, 1940 | Arizona State 42, New Mexico State 6 | Box score |
| Oct 19, 1940 | Harvard 6, Army 6 | Box score |
| Oct 19, 1940 | Baylor 7, Villanova 0 | Box score |
| Oct 19, 1940 | 8Boston College 60, Idaho 0 | Box score |
| Oct 19, 1940 | California 9, UCLA 7 | Box score |
| Oct 19, 1940 | Colorado 33, Colorado State 14 | Box score |
| Oct 19, 1940 | Columbia 19, Georgia 13 | Box score |
| Oct 19, 1940 | 1Cornell 33, Syracuse 6 | Box score |
| Oct 19, 1940 | Davidson 27, Sewanee 20 | Box score |
| Oct 19, 1940 | Denver 41, Wyoming 9 | Box score |
| Oct 19, 1940 | Duke 13, Colgate 0 | Box score |
| Oct 19, 1940 | Florida 19, Maryland 0 | Box score |
| Oct 19, 1940 | 11Fordham 24, Pittsburgh 12 | Box score |
| Oct 19, 1940 | Georgetown 46, Virginia Tech 4 | Box score |
| Oct 19, 1940 | Georgia Tech 19, Vanderbilt 0 | Box score |
| Oct 19, 1940 | Holy Cross 13, New York University 7 | Box score |
| Oct 19, 1940 | Indiana 10, 20Iowa 6upset | Box score |
| Oct 19, 1940 | Kentucky 24, George Washington 0 | Box score |
| Oct 19, 1940 | Creighton 27, Marquette 27 | Box score |
| Oct 19, 1940 | 3Michigan 28, Illinois 0 | Box score |
| Oct 19, 1940 | 7Minnesota 13, 15Ohio State 7 | Box score |
| Oct 19, 1940 | 13Ole Miss 14, Duquesne 6 | Box score |
| Oct 19, 1940 | Missouri 30, Iowa State 14 | Box score |
| Oct 19, 1940 | Navy 19, Drake 0 | Box score |
| Oct 19, 1940 | Nebraska 53, Kansas 2 | Box score |
| Oct 19, 1940 | North Carolina 13, NC State 7 | Box score |
| Oct 19, 1940 | 4Northwestern 27, Wisconsin 7 | Box score |
| Oct 19, 1940 | 6Notre Dame 61, Carnegie Mellon 0 | Box score |
| Oct 19, 1940 | Oklahoma 14, Kansas State 0 | Box score |
| Oct 19, 1940 | Oklahoma State 53, Washington St. Louis 12 | Box score |
| Oct 19, 1940 | 9Pennsylvania 46, Princeton 28 | Box score |
| Oct 19, 1940 | Saint Mary’s (CA) 18, Loyola Marymount 7 | Box score |
| Oct 19, 1940 | 17USC 13, Oregon 0 | Box score |
| Oct 19, 1940 | SMU 20, Auburn 13 | Box score |
| Oct 19, 1940 | 10Stanford 26, 19Washington State 14 | Box score |
| Oct 19, 1940 | 5Tennessee 27, Alabama 12 | Box score |
| Oct 19, 1940 | 14Texas 21, Arkansas 0 | Box score |
| Oct 19, 1940 | 2Texas A&M 21, TCU 7 | Box score |
| Oct 19, 1940 | UTEP 9, New Mexico 7 | Box score |
| Oct 19, 1940 | Tulane 15, Rice 6 | Box score |
| Oct 19, 1940 | Utah State 7, Utah 0upset | Box score |
| Oct 19, 1940 | VMI 7, Virginia 0 | Box score |
| Oct 19, 1940 | 16Washington 19, 18Oregon State 0 | Box score |
| Oct 19, 1940 | Washington and Lee 3, Richmond 0 | Box score |
| Oct 19, 1940 | William & Mary 41, Hampden Sydney 0 | Box score |
| Oct 19, 1940 | Yale 13, Dartmouth 7 | Box score |