| Sep 25, 1912 | Carlisle 45, Lebanon Valley 0 | Box score |
| Sep 25, 1912 | Lehigh 33, Albright 0 | Box score |
| Sep 25, 1912 | Yale 10, Wesleyan (CT) 3 | Box score |
| Sep 28, 1912 | Georgia Tech 0, 11th Cavalry 0 | Box score |
| Sep 28, 1912 | Alabama 52, Marion 0 | Box score |
| Sep 28, 1912 | Arkansas 39, Henderson State 6 | Box score |
| Sep 28, 1912 | Brown 3, Colby 0 | Box score |
| Sep 28, 1912 | Bucknell 41, Harry Hillman Academy 0 | Box score |
| Sep 28, 1912 | Carlisle 35, Dickinson 0 | Box score |
| Sep 28, 1912 | Colorado 20, Colorado Alumni 0 | Box score |
| Sep 28, 1912 | Colorado College 20, Colorado College Alumni 3 | Box score |
| Sep 28, 1912 | Colorado School of Mines 23, Colorado Springs High 0 | Box score |
| Sep 28, 1912 | Dartmouth 41, Norwich 9 | Box score |
| Sep 28, 1912 | Davidson 39, Westminster (Pennsylvania) 0 | Box score |
| Sep 28, 1912 | Georgetown 39, Randolph Macon 0 | Box score |
| Sep 28, 1912 | Harvard 7, Maine 0 | Box score |
| Sep 28, 1912 | Indiana 20, DePauw 0 | Box score |
| Sep 28, 1912 | Kansas State 19, Southwestern (Kansas) 7 | Box score |
| Sep 28, 1912 | Lafayette 20, Muhlenberg 3 | Box score |
| Sep 28, 1912 | Lehigh 45, Delaware 0 | Box score |
| Sep 28, 1912 | Mercer 6, Stetson 0 | Box score |
| Sep 28, 1912 | Mississippi College 44, Vicksburg A.C. 0 | Box score |
| Sep 28, 1912 | Missouri 55, Central Methodist 7 | Box score |
| Sep 28, 1912 | Pennsylvania 25, Gettysburg 0 | Box score |
| Sep 28, 1912 | Pittsburgh 22, Ohio Northern 0 | Box score |
| Sep 28, 1912 | Princeton 65, Stevens 0 | Box score |
| Sep 28, 1912 | Samford 8, Jacksonville State 0 | Box score |
| Sep 28, 1912 | South Dakota 10, Minnesota 0upset | Box score |
| Sep 28, 1912 | Swarthmore 40, Johns Hopkins 6 | Box score |
| Sep 28, 1912 | Syracuse 12, Hobart 0 | Box score |
| Sep 28, 1912 | Vanderbilt 105, Bethel 0 | Box score |
| Sep 28, 1912 | Wake Forest 33, North Carolina Medical 0 | Box score |
| Sep 28, 1912 | Washburn 12, Denver 0upset | Box score |
| Sep 28, 1912 | Washington & Jefferson 52, Geneva 7 | Box score |
| Sep 28, 1912 | Washington and Lee 7, Virginia Medical 0 | Box score |
| Sep 30, 1912 | Virginia Tech 40, Roanoke 0 | Box score |