| Sep 8, 2011 | Hampton 23, Florida A&M 17 | Box score |
| Sep 8, 2011 | Tennessee Tech 56, Maryville (TN) 7 | Box score |
| Sep 10, 2011 | Illinois 56, South Dakota State 3 | Box score |
| Sep 10, 2011 | Old Dominion 40, Georgia State 17 | Box score |
| Sep 10, 2011 | North Carolina Central 42, Central State 3 | Box score |
| Sep 10, 2011 | New Hampshire 48, Lehigh 41 | Box score |
| Sep 10, 2011 | Holy Cross 37, Colgate 7 | Box score |
| Sep 10, 2011 | Pittsburgh 35, Maine 29 | Box score |
| Sep 10, 2011 | 19West Virginia 55, Norfolk State 12 | Box score |
| Sep 10, 2011 | Campbell 76, Apprentice School 0 | Box score |
| Sep 10, 2011 | Duquesne 22, Dayton 13upset | Box score |
| Sep 10, 2011 | Eastern Michigan 14, Alabama State 7 | Box score |
| Sep 10, 2011 | Bryant 27, American International 16 | Box score |
| Sep 10, 2011 | Presbyterian 38, North Greenville 21 | Box score |
| Sep 10, 2011 | William & Mary 24, VMI 7 | Box score |
| Sep 10, 2011 | Colorado State 33, Northern Colorado 14 | Box score |
| Sep 10, 2011 | Indiana State 48, Butler 34 | Box score |
| Sep 10, 2011 | McMurry 24, UTSA 21upset | Box score |
| Sep 10, 2011 | Montana State 38, UC Davis 14 | Box score |
| Sep 10, 2011 | Montana 37, Cal Poly 23 | Box score |
| Sep 10, 2011 | Southern Utah 35, Sacramento State 14 | Box score |
| Sep 10, 2011 | Howard 30, Morehouse 27 | Box score |
| Sep 10, 2011 | Northwestern 42, Eastern Illinois 21 | Box score |
| Sep 10, 2011 | Clemson 35, Wofford 27 | Box score |
| Sep 10, 2011 | App State 58, North Carolina A&T 6 | Box score |
| Sep 10, 2011 | South Carolina State 26, Bethune-Cookman 18 | Box score |
| Sep 10, 2011 | Western Illinois 35, Jacksonville 21 | Box score |
| Sep 10, 2011 | Youngstown State 77, Valparaiso 13 | Box score |
| Sep 10, 2011 | Syracuse 21, Rhode Island 14 | Box score |
| Sep 10, 2011 | South Alabama 30, Lamar 8 | Box score |
| Sep 10, 2011 | Idaho 44, North Dakota 14 | Box score |
| Sep 10, 2011 | South Dakota 30, Eastern Washington 17 | Box score |
| Sep 10, 2011 | Murray State 39, Mississippi Valley State 0 | Box score |
| Sep 10, 2011 | Georgetown 14, Lafayette 13 | Box score |
| Sep 10, 2011 | Delaware 28, West Chester 17 | Box score |
| Sep 10, 2011 | 5Florida State 62, Charleston Southern 10 | Box score |
| Sep 10, 2011 | Ole Miss 42, Southern Illinois 24 | Box score |
| Sep 10, 2011 | Chattanooga 38, Jacksonville State 17 | Box score |
| Sep 10, 2011 | James Madison 14, Central Connecticut 9 | Box score |
| Sep 10, 2011 | Richmond 21, Wagner 6 | Box score |
| Sep 10, 2011 | Georgia Southern 62, Tusculum 21 | Box score |
| Sep 10, 2011 | Idaho State 44, Western Colorado 7 | Box score |
| Sep 10, 2011 | Coastal Carolina 20, Catawba 3 | Box score |
| Sep 10, 2011 | Bucknell 28, Marist 14 | Box score |
| Sep 10, 2011 | Buffalo 35, Stony Brook 7 | Box score |
| Sep 10, 2011 | Delaware State 31, Shaw 27 | Box score |
| Sep 10, 2011 | Eastern Kentucky 28, Missouri State 24 | Box score |
| Sep 10, 2011 | Furman 16, The Citadel 6 | Box score |
| Sep 10, 2011 | Western Carolina 52, Mars Hill 31 | Box score |
| Sep 10, 2011 | Wyoming 45, Texas State 10 | Box score |
| Sep 10, 2011 | Northern Arizona 58, Fort Lewis 13 | Box score |
| Sep 10, 2011 | Towson 31, Villanova 10upset | Box score |
| Sep 10, 2011 | Bowling Green 58, Morgan State 13 | Box score |
| Sep 10, 2011 | Ohio 30, Gardner-Webb 3 | Box score |
| Sep 10, 2011 | Arkansas–Pine Bluff 27, Alcorn State 20 | Box score |
| Sep 10, 2011 | Davidson 28, Lenoir Rhyne 10 | Box score |
| Sep 10, 2011 | Drake 28, Des Moines 21 | Box score |
| Sep 10, 2011 | Elon 42, Concord 10 | Box score |
| Sep 10, 2011 | Jackson State 35, Tennessee State 29 | Box score |
| Sep 10, 2011 | Liberty 38, Robert Morris 7 | Box score |
| Sep 10, 2011 | Louisiana Tech 48, Central Arkansas 42 | Box score |
| Sep 10, 2011 | UL Monroe 35, Grambling 7 | Box score |
| Sep 10, 2011 | North Dakota State 56, Saint Francis 3 | Box score |
| Sep 10, 2011 | Samford 48, Stillman 6 | Box score |
| Sep 10, 2011 | Southern 21, Alabama A&M 6 | Box score |
| Sep 10, 2011 | Northern Iowa 34, Stephen F. Austin 23 | Box score |
| Sep 10, 2011 | Western Michigan 38, Nicholls 7 | Box score |
| Sep 10, 2011 | Illinois State 52, Morehead State 21 | Box score |
| Sep 10, 2011 | 2LSU 49, Northwestern State 3 | Box score |
| Sep 10, 2011 | Utah State 54, Weber State 17 | Box score |
| Sep 10, 2011 | SE Louisiana 63, Savannah State 6 | Box score |
| Sep 10, 2011 | Prairie View A&M 37, Texas Southern 34 | Box score |
| Sep 10, 2011 | San Diego 30, Western New Mexico 10 | Box score |