| Oct 11, 2001 | 22Maryland 20, 15Georgia Tech 17upset | Box score |
| Oct 13, 2001 | 2Miami 49, 14Florida State 27 | Box score |
| Oct 13, 2001 | Northwestern 23, Minnesota 17 | Box score |
| Oct 13, 2001 | 16Clemson 45, NC State 37 | Box score |
| Oct 13, 2001 | Syracuse 42, Pittsburgh 10 | Box score |
| Oct 13, 2001 | Rice 21, Navy 13 | Box score |
| Oct 13, 2001 | Michigan State 31, Iowa 28 | Box score |
| Oct 13, 2001 | 12Michigan 24, 17Purdue 10 | Box score |
| Oct 13, 2001 | Ole Miss 27, Alabama 24 | Box score |
| Oct 13, 2001 | 11Texas 45, Oklahoma State 17 | Box score |
| Oct 13, 2001 | East Carolina 49, Army 26 | Box score |
| Oct 13, 2001 | Wake Forest 42, Duke 35 | Box score |
| Oct 13, 2001 | Marshall 34, Buffalo 14 | Box score |
| Oct 13, 2001 | Ohio 34, Central Michigan 3 | Box score |
| Oct 13, 2001 | Western Michigan 37, Bowling Green 28 | Box score |
| Oct 13, 2001 | North Carolina 30, Virginia 24 | Box score |
| Oct 13, 2001 | Illinois 35, Indiana 14 | Box score |
| Oct 13, 2001 | Iowa State 20, Missouri 14 | Box score |
| Oct 13, 2001 | Miami (OH) 30, Akron 27 | Box score |
| Oct 13, 2001 | 19Georgia 30, Vanderbilt 14 | Box score |
| Oct 13, 2001 | 4Nebraska 48, Baylor 7 | Box score |
| Oct 13, 2001 | Kent State 44, Northern Illinois 34 | Box score |
| Oct 13, 2001 | Notre Dame 34, West Virginia 24 | Box score |
| Oct 13, 2001 | Troy 21, Mississippi State 9upset | Box score |
| Oct 13, 2001 | 18BYU 24, New Mexico 20 | Box score |
| Oct 13, 2001 | Air Force 24, Wyoming 13 | Box score |
| Oct 13, 2001 | Arkansas State 26, Louisiana 20 | Box score |
| Oct 13, 2001 | Arkansas 10, 9South Carolina 7upset | Box score |
| Oct 13, 2001 | 5Oregon 48, California 7 | Box score |
| Oct 13, 2001 | 7UCLA 35, 10Washington 13 | Box score |
| Oct 13, 2001 | 20Colorado 31, 25Texas A&M 21 | Box score |
| Oct 13, 2001 | Wisconsin 20, 21Ohio State 17upset | Box score |
| Oct 13, 2001 | Tulane 48, TCU 22upset | Box score |
| Oct 13, 2001 | Temple 30, Rutgers 5 | Box score |
| Oct 13, 2001 | North Texas 24, Middle Tennessee 21upset | Box score |
| Oct 13, 2001 | Louisiana Tech 45, Nevada 42 | Box score |
| Oct 13, 2001 | Cincinnati 31, UAB 17 | Box score |
| Oct 13, 2001 | SMU 24, San José State 17upset | Box score |
| Oct 13, 2001 | Washington State 45, 23Stanford 39upset | Box score |
| Oct 13, 2001 | Ball State 35, Eastern Michigan 14 | Box score |
| Oct 13, 2001 | USC 48, Arizona State 17 | Box score |
| Oct 13, 2001 | 6Virginia Tech 34, Boston College 20 | Box score |
| Oct 13, 2001 | South Florida 40, UConn 21 | Box score |
| Oct 13, 2001 | LSU 29, Kentucky 25 | Box score |
| Oct 13, 2001 | 3Oklahoma 38, Kansas 10 | Box score |
| Oct 13, 2001 | UNLV 31, San Diego State 3 | Box score |
| Oct 13, 2001 | Auburn 23, 1Florida 20upset | Box score |
| Oct 13, 2001 | New Mexico State 46, Idaho 39 | Box score |
| Oct 13, 2001 | Memphis 52, Houston 33 | Box score |
| Oct 13, 2001 | Texas Tech 38, 24Kansas State 19upset | Box score |
| Oct 13, 2001 | Boise State 41, Tulsa 10 | Box score |
| Oct 13, 2001 | 8Fresno State 25, Colorado State 22 | Box score |
| Oct 13, 2001 | Oregon State 38, Arizona 3 | Box score |
| Oct 14, 2001 | Hawai’i 66, UTEP 7 | Box score |