| Sep 27, 2001 | 1Miami 43, Pittsburgh 21 | Box score |
| Sep 29, 2001 | Boston College 31, Army 10 | Box score |
| Sep 29, 2001 | Maryland 32, West Virginia 20 | Box score |
| Sep 29, 2001 | North Carolina 17, NC State 9upset | Box score |
| Sep 29, 2001 | 3Oklahoma 38, 11Kansas State 37 | Box score |
| Sep 29, 2001 | 8Virginia Tech 46, UCF 14 | Box score |
| Sep 29, 2001 | 16Northwestern 27, 23Michigan State 26 | Box score |
| Sep 29, 2001 | Ohio State 27, Indiana 14 | Box score |
| Sep 29, 2001 | 24Purdue 35, Minnesota 28 | Box score |
| Sep 29, 2001 | Iowa 24, Penn State 18 | Box score |
| Sep 29, 2001 | 4Nebraska 36, Missouri 3 | Box score |
| Sep 29, 2001 | 15South Carolina 37, Alabama 36 | Box score |
| Sep 29, 2001 | Virginia 31, Duke 10 | Box score |
| Sep 29, 2001 | Ole Miss 42, Kentucky 31 | Box score |
| Sep 29, 2001 | Syracuse 44, East Carolina 30 | Box score |
| Sep 29, 2001 | Iowa State 41, Baylor 0 | Box score |
| Sep 29, 2001 | Louisville 38, Memphis 21 | Box score |
| Sep 29, 2001 | Miami (OH) 28, Ball State 20 | Box score |
| Sep 29, 2001 | Utah 37, New Mexico 16 | Box score |
| Sep 29, 2001 | Colorado State 42, Wyoming 14 | Box score |
| Sep 29, 2001 | 2Florida 52, 21Mississippi State 0 | Box score |
| Sep 29, 2001 | Clemson 47, 9Georgia Tech 44upset | Box score |
| Sep 29, 2001 | 17Michigan 45, 22Illinois 20 | Box score |
| Sep 29, 2001 | 12UCLA 38, 19Oregon State 7 | Box score |
| Sep 29, 2001 | Texas A&M 24, Notre Dame 3 | Box score |
| Sep 29, 2001 | 13Washington 31, California 28 | Box score |
| Sep 29, 2001 | Akron 14, Kent State 10 | Box score |
| Sep 29, 2001 | Western Michigan 31, Eastern Michigan 10 | Box score |
| Sep 29, 2001 | Stanford 21, USC 16 | Box score |
| Sep 29, 2001 | Georgia 34, Arkansas 23 | Box score |
| Sep 29, 2001 | 18Florida State 48, Wake Forest 24 | Box score |
| Sep 29, 2001 | South Florida 28, North Texas 10 | Box score |
| Sep 29, 2001 | UConn 20, Rutgers 19upset | Box score |
| Sep 29, 2001 | Auburn 24, Vanderbilt 21 | Box score |
| Sep 29, 2001 | 5Texas 42, Texas Tech 7 | Box score |
| Sep 29, 2001 | Marshall 37, Bowling Green 31 | Box score |
| Sep 29, 2001 | Central Michigan 16, Buffalo 8 | Box score |
| Sep 29, 2001 | New Mexico State 31, UL Monroe 0 | Box score |
| Sep 29, 2001 | 20BYU 35, UNLV 31 | Box score |
| Sep 29, 2001 | Southern Miss 3, UAB 0 | Box score |
| Sep 29, 2001 | 25Toledo 41, Northern Illinois 20 | Box score |
| Sep 29, 2001 | 7Tennessee 26, 14LSU 18 | Box score |
| Sep 29, 2001 | TCU 34, Houston 17 | Box score |
| Sep 29, 2001 | Middle Tennessee 26, Louisiana 9 | Box score |
| Sep 29, 2001 | 6Oregon 38, Utah State 21 | Box score |
| Sep 29, 2001 | UTEP 26, Tulsa 10 | Box score |
| Sep 29, 2001 | Arizona State 53, San José State 15 | Box score |
| Sep 29, 2001 | Washington State 48, Arizona 21 | Box score |
| Sep 29, 2001 | Boise State 45, Idaho 13 | Box score |
| Sep 29, 2001 | 10Fresno State 38, Louisiana Tech 28 | Box score |
| Sep 29, 2001 | Air Force 45, San Diego State 21 | Box score |
| Sep 30, 2001 | Rice 27, Hawai’i 24 | Box score |