| Sep 20, 2001 | South Carolina 16, Mississippi State 14 | Box score |
| Sep 20, 2001 | Nebraska 48, Rice 3 | Box score |
| Sep 22, 2001 | North Carolina 41, Florida State 9upset | Box score |
| Sep 22, 2001 | Virginia Tech 50, Rutgers 0 | Box score |
| Sep 22, 2001 | Boston College 38, Navy 21 | Box score |
| Sep 22, 2001 | Michigan 38, Western Michigan 21 | Box score |
| Sep 22, 2001 | Wisconsin 18, Penn State 6 | Box score |
| Sep 22, 2001 | Illinois 34, Louisville 10 | Box score |
| Sep 22, 2001 | Purdue 33, Akron 14 | Box score |
| Sep 22, 2001 | Florida 44, Kentucky 10 | Box score |
| Sep 22, 2001 | Texas A&M 21, Oklahoma State 7 | Box score |
| Sep 22, 2001 | Buffalo 37, UConn 20 | Box score |
| Sep 22, 2001 | Iowa State 31, Ohio 28 | Box score |
| Sep 22, 2001 | West Virginia 34, Kent State 14 | Box score |
| Sep 22, 2001 | Toledo 52, Central Michigan 28 | Box score |
| Sep 22, 2001 | Miami (OH) 21, Cincinnati 14 | Box score |
| Sep 22, 2001 | Kansas State 64, New Mexico State 0 | Box score |
| Sep 22, 2001 | Michigan State 17, Notre Dame 10 | Box score |
| Sep 22, 2001 | Fresno State 37, Tulsa 18 | Box score |
| Sep 22, 2001 | UCLA 13, Ohio State 6 | Box score |
| Sep 22, 2001 | Colorado 27, Kansas 16 | Box score |
| Sep 22, 2001 | Maryland 27, Wake Forest 20 | Box score |
| Sep 22, 2001 | Washington 53, Idaho 3 | Box score |
| Sep 22, 2001 | Alabama 31, Arkansas 10 | Box score |
| Sep 22, 2001 | UCF 36, Tulane 29 | Box score |
| Sep 22, 2001 | Nevada 28, Hawai’i 20 | Box score |
| Sep 22, 2001 | UAB 55, Army 3 | Box score |
| Sep 22, 2001 | Utah 28, Indiana 26 | Box score |
| Sep 22, 2001 | Washington State 51, California 20 | Box score |
| Sep 22, 2001 | Virginia 26, Clemson 24upset | Box score |
| Sep 22, 2001 | Northwestern 44, Duke 7 | Box score |
| Sep 22, 2001 | Bowling Green 42, Temple 23 | Box score |
| Sep 22, 2001 | Southern Miss 35, Louisiana 10 | Box score |
| Sep 22, 2001 | NC State 26, SMU 17 | Box score |
| Sep 22, 2001 | San Diego State 14, Colorado State 7upset | Box score |
| Sep 22, 2001 | Baylor 16, New Mexico 13 | Box score |
| Sep 22, 2001 | Middle Tennessee 38, UL Monroe 20 | Box score |
| Sep 22, 2001 | Syracuse 31, Auburn 14 | Box score |
| Sep 22, 2001 | Memphis 17, South Florida 9 | Box score |
| Sep 22, 2001 | Boise State 42, UTEP 17 | Box score |
| Sep 22, 2001 | Texas Tech 42, North Texas 14 | Box score |
| Sep 22, 2001 | Texas 53, Houston 26 | Box score |
| Sep 22, 2001 | Wyoming 43, Utah State 42 | Box score |
| Sep 22, 2001 | Arizona 38, UNLV 21 | Box score |
| Sep 22, 2001 | Stanford 51, Arizona State 28 | Box score |
| Sep 22, 2001 | Oregon 24, USC 22 | Box score |