| Oct 4, 1974 | 11Auburn 3, 16Miami 0 | Box score |
| Oct 5, 1974 | 3Alabama 35, Ole Miss 21 | Box score |
| Oct 5, 1974 | 12Arizona 42, UTEP 13 | Box score |
| Oct 5, 1974 | 18Arizona State 16, Wyoming 10 | Box score |
| Oct 5, 1974 | 20Arkansas 49, TCU 0 | Box score |
| Oct 5, 1974 | Baylor 21, Florida State 17 | Box score |
| Oct 5, 1974 | Boston College 37, Navy 0 | Box score |
| Oct 5, 1974 | Colorado State 33, BYU 33 | Box score |
| Oct 5, 1974 | California 31, 14Illinois 14upset | Box score |
| Oct 5, 1974 | Clemson 28, Georgia 24 | Box score |
| Oct 5, 1974 | Colorado 28, Air Force 27 | Box score |
| Oct 5, 1974 | Duke 16, Purdue 14 | Box score |
| Oct 5, 1974 | 13Florida 24, LSU 14 | Box score |
| Oct 5, 1974 | Fresno State 9, New Mexico State 7upset | Box score |
| Oct 5, 1974 | Furman 24, Richmond 14upset | Box score |
| Oct 5, 1974 | Georgia Tech 28, Virginia 24 | Box score |
| Oct 5, 1974 | Hawai’i 23, Pacific 14upset | Box score |
| Oct 5, 1974 | Holy Cross 14, Dartmouth 3 | Box score |
| Oct 5, 1974 | Houston 24, South Carolina 14 | Box score |
| Oct 5, 1974 | Iowa State 27, New Mexico 3 | Box score |
| Oct 5, 1974 | Kansas 28, 5Texas A&M 10upset | Box score |
| Oct 5, 1974 | Kent State 28, Western Michigan 6 | Box score |
| Oct 5, 1974 | Lamar 38, Louisiana 13 | Box score |
| Oct 5, 1974 | Louisville 14, Wichita State 7 | Box score |
| Oct 5, 1974 | Maryland 31, Syracuse 0 | Box score |
| Oct 5, 1974 | Miami (OH) 14, Kentucky 10 | Box score |
| Oct 5, 1974 | 4Michigan 27, Stanford 16 | Box score |
| Oct 5, 1974 | Mississippi State 21, Kansas State 16 | Box score |
| Oct 5, 1974 | 6Nebraska 54, Minnesota 0 | Box score |
| Oct 5, 1974 | North Carolina 45, 17Pittsburgh 29upset | Box score |
| Oct 5, 1974 | 8NC State 24, East Carolina 20 | Box score |
| Oct 5, 1974 | Drake 24, North Texas 24 | Box score |
| Oct 5, 1974 | Northwestern 14, Oregon 10 | Box score |
| Oct 5, 1974 | 7Notre Dame 19, Michigan State 14 | Box score |
| Oct 5, 1974 | Ohio 31, Northern Illinois 14 | Box score |
| Oct 5, 1974 | 1Ohio State 42, Washington State 7 | Box score |
| Oct 5, 1974 | 2Oklahoma 63, Wake Forest 0 | Box score |
| Oct 5, 1974 | 15Penn State 21, Army 14 | Box score |
| Oct 5, 1974 | Pennsylvania 14, Brown 9 | Box score |
| Oct 5, 1974 | Princeton 40, Columbia 13 | Box score |
| Oct 5, 1974 | Rutgers 24, Harvard 21upset | Box score |
| Oct 5, 1974 | San José State 27, Long Beach State 17 | Box score |
| Oct 5, 1974 | 9USC 41, Iowa 3 | Box score |
| Oct 5, 1974 | Southern Illinois 38, Dayton 16upset | Box score |
| Oct 5, 1974 | SMU 37, Oregon State 30 | Box score |
| Oct 5, 1974 | Temple 31, Marshall 10 | Box score |
| Oct 5, 1974 | Tennessee 17, Tulsa 10 | Box score |
| Oct 5, 1974 | 19Texas 35, Washington 21 | Box score |
| Oct 5, 1974 | 10Texas Tech 14, Oklahoma State 13 | Box score |
| Oct 5, 1974 | Toledo 24, Bowling Green 19 | Box score |
| Oct 5, 1974 | UCLA 27, Utah 14 | Box score |
| Oct 5, 1974 | VMI 22, Virginia Tech 17 | Box score |
| Oct 5, 1974 | West Texas 31, Southern Miss 0 | Box score |
| Oct 5, 1974 | West Virginia 24, Indiana 0 | Box score |
| Oct 5, 1974 | William & Mary 16, The Citadel 12 | Box score |
| Oct 5, 1974 | Wisconsin 59, Missouri 20 | Box score |
| Oct 5, 1974 | Yale 30, Colgate 7 | Box score |