1916: Week 6
52 games. Winners are listed first; numbers before names are AP ranks going in.
FBS vs. FBS
| Oct 18, 1916 | Maryland 15, VMI 9 | Box score |
| Oct 19, 1916 | NC State 6, Wake Forest 0 | Box score |
| Oct 20, 1916 | Auburn 28, Clemson 0 | Box score |
| Oct 20, 1916 | Yale 19, Virginia Tech 0 | Box score |
| Oct 21, 1916 | Alabama 16, Florida 0 | Box score |
| Oct 21, 1916 | Davidson 7, The Citadel 7 | Box score |
| Oct 21, 1916 | Colorado College 54, Colorado School of Mines 0 | Box score |
| Oct 21, 1916 | Cornell 19, Bucknell 0 | Box score |
| Oct 21, 1916 | Denver 7, Colorado 0 | Box score |
| Oct 21, 1916 | Drake 13, Washington St. Louis 0upset | Box score |
| Oct 21, 1916 | Georgetown 10, Dartmouth 0 | Box score |
| Oct 21, 1916 | Georgia 13, Virginia 7 | Box score |
| Oct 21, 1916 | Georgia Tech 10, North Carolina 6 | Box score |
| Oct 21, 1916 | Iowa 24, Purdue 6 | Box score |
| Oct 21, 1916 | Missouri 0, Iowa State 0 | Box score |
| Oct 21, 1916 | LSU 50, Mississippi College 7 | Box score |
| Oct 21, 1916 | Michigan 9, Michigan State 0 | Box score |
| Oct 21, 1916 | Navy 12, West Virginia 7 | Box score |
| Oct 21, 1916 | Nebraska 17, Oregon State 7 | Box score |
| Oct 21, 1916 | Northwestern 10, Chicago 0upset | Box score |
| Oct 21, 1916 | Ohio State 7, Illinois 6upset | Box score |
| Oct 21, 1916 | Oregon 39, California 14 | Box score |
| Oct 21, 1916 | Pennsylvania 15, Penn State 0upset | Box score |
| Oct 21, 1916 | Pittsburgh 30, Syracuse 0 | Box score |
| Oct 21, 1916 | Princeton 33, Lafayette 0 | Box score |
| Oct 21, 1916 | Rice 54, Southwestern U 0 | Box score |
| Oct 21, 1916 | Kentucky 0, Sewanee 0 | Box score |
| Oct 21, 1916 | Tennessee 26, South Carolina 0 | Box score |
| Oct 21, 1916 | Texas 21, Oklahoma 7 | Box score |
| Oct 21, 1916 | Texas A&M 62, SMU 0 | Box score |
| Oct 21, 1916 | Vanderbilt 35, Ole Miss 0 | Box score |
| Oct 21, 1916 | Wisconsin 13, Haskell 0 | Box score |
| Oct 21, 1916 | Wyoming 23, Utah State 10upset | Box score |
Everyone else
| Oct 21, 1916 | Arkansas 60, Missouri–Rolla 0 | Box score |
| Oct 21, 1916 | Army 53, Trinity (CT) 0 | Box score |
| Oct 21, 1916 | Baylor 47, Howard Payne 0 | Box score |
| Oct 21, 1916 | Brown 20, Williams 0 | Box score |
| Oct 21, 1916 | Colgate 33, Rhode Island 0 | Box score |
| Oct 21, 1916 | Erskine 12, Wofford 7 | Box score |
| Oct 21, 1916 | Furman 21, Georgia Tech B 10 | Box score |
| Oct 21, 1916 | Harvard 47, Massachusetts 0 | Box score |
| Oct 21, 1916 | Kansas State 13, Emporia State 3 | Box score |
| Oct 21, 1916 | Lehigh 3, Lebanon Valley 3 | Box score |
| Oct 21, 1916 | Minnesota 81, South Dakota 0 | Box score |
| Oct 21, 1916 | Mississippi State 13, Transylvania 0 | Box score |
| Oct 21, 1916 | Oklahoma State 117, Southwestern Oklahoma State 0 | Box score |
| Oct 21, 1916 | Tufts 12, Indiana 10upset | Box score |
| Oct 21, 1916 | Tulane 39, Jefferson 3 | Box score |
| Oct 21, 1916 | Utah 27, USC 12 | Box score |
| Oct 21, 1916 | Washington 62, Bremerton Navy 0 | Box score |
| Oct 21, 1916 | Washington & Jefferson 12, Westminster (Pennsylvania) 0 | Box score |
| Oct 21, 1916 | Washington and Lee 30, Roanoke 0 | Box score |