| Oct 25, 2001 | 1Miami 45, West Virginia 3 | Box score |
| Oct 26, 2001 | Hawai’i 38, 18Fresno State 34upset | Box score |
| Oct 27, 2001 | Clemson 21, Wake Forest 14 | Box score |
| Oct 27, 2001 | 3Nebraska 20, 2Oklahoma 10upset | Box score |
| Oct 27, 2001 | Pittsburgh 33, Temple 7 | Box score |
| Oct 27, 2001 | Syracuse 22, 5Virginia Tech 14upset | Box score |
| Oct 27, 2001 | Penn State 29, Ohio State 27 | Box score |
| Oct 27, 2001 | Michigan State 42, Wisconsin 28 | Box score |
| Oct 27, 2001 | 24Purdue 32, Northwestern 27 | Box score |
| Oct 27, 2001 | Arkansas 42, 17Auburn 17upset | Box score |
| Oct 27, 2001 | Vanderbilt 42, Duke 28 | Box score |
| Oct 27, 2001 | Kent State 24, Ohio 14upset | Box score |
| Oct 27, 2001 | Army 42, Tulane 35 | Box score |
| Oct 27, 2001 | Northern Illinois 33, Central Michigan 24 | Box score |
| Oct 27, 2001 | Ball State 10, UConn 5 | Box score |
| Oct 27, 2001 | NC State 24, Virginia 0 | Box score |
| Oct 27, 2001 | 7Texas 35, Missouri 16 | Box score |
| Oct 27, 2001 | UAB 17, Memphis 14 | Box score |
| Oct 27, 2001 | Texas A&M 24, Iowa State 21 | Box score |
| Oct 27, 2001 | Louisville 28, Cincinnati 13 | Box score |
| Oct 27, 2001 | Miami (OH) 25, Western Michigan 11 | Box score |
| Oct 27, 2001 | Louisiana Tech 41, Rice 38 | Box score |
| Oct 27, 2001 | Colorado State 19, Utah 17 | Box score |
| Oct 27, 2001 | Texas Tech 63, Baylor 19 | Box score |
| Oct 27, 2001 | Arkansas State 34, Idaho 31 | Box score |
| Oct 27, 2001 | Eastern Michigan 24, Buffalo 20 | Box score |
| Oct 27, 2001 | Middle Tennessee 39, New Mexico State 35 | Box score |
| Oct 27, 2001 | SMU 40, UTEP 14 | Box score |
| Oct 27, 2001 | Southern Miss 58, Houston 14 | Box score |
| Oct 27, 2001 | 20Stanford 38, 4UCLA 28upset | Box score |
| Oct 27, 2001 | 19Florida State 52, 10Maryland 31upset | Box score |
| Oct 27, 2001 | 6Florida 24, 15Georgia 10 | Box score |
| Oct 27, 2001 | 8Michigan 32, Iowa 26 | Box score |
| Oct 27, 2001 | Kansas State 40, Kansas 6 | Box score |
| Oct 27, 2001 | Oregon State 19, California 10 | Box score |
| Oct 27, 2001 | San José State 63, Tulsa 27 | Box score |
| Oct 27, 2001 | Louisiana 17, UL Monroe 12 | Box score |
| Oct 27, 2001 | Utah State 30, UCF 27 | Box score |
| Oct 27, 2001 | New Mexico 52, Air Force 33 | Box score |
| Oct 27, 2001 | 9Tennessee 17, 12South Carolina 10 | Box score |
| Oct 27, 2001 | UNLV 47, Wyoming 26 | Box score |
| Oct 27, 2001 | USC 41, Arizona 34 | Box score |
| Oct 27, 2001 | 25Colorado 22, Oklahoma State 19 | Box score |
| Oct 27, 2001 | 11Oregon 24, 14Washington State 17 | Box score |
| Oct 27, 2001 | Marshall 50, Akron 33 | Box score |
| Oct 27, 2001 | Toledo 21, Navy 20 | Box score |
| Oct 27, 2001 | Boston College 21, Notre Dame 17 | Box score |
| Oct 27, 2001 | Boise State 49, Nevada 7 | Box score |
| Oct 27, 2001 | Ole Miss 35, LSU 24 | Box score |
| Oct 27, 2001 | 16BYU 59, San Diego State 21 | Box score |
| Oct 27, 2001 | 13Washington 33, Arizona State 31 | Box score |