| Sep 17, 1998 | Air Force 30, Colorado State 27 | Box score |
| Sep 19, 1998 | 16Arizona 35, Iowa 11 | Box score |
| Sep 19, 1998 | Arizona State 34, North Texas 15 | Box score |
| Sep 19, 1998 | Arkansas 44, SMU 17 | Box score |
| Sep 19, 1998 | Army 37, Cincinnati 20 | Box score |
| Sep 19, 1998 | Baylor 33, 20NC State 30upset | Box score |
| Sep 19, 1998 | Boston College 31, Temple 7 | Box score |
| Sep 19, 1998 | California 13, Oklahoma 12 | Box score |
| Sep 19, 1998 | 15Colorado 25, Utah State 6 | Box score |
| Sep 19, 1998 | East Carolina 21, Ohio 14 | Box score |
| Sep 19, 1998 | 11Florida State 62, Duke 13 | Box score |
| Sep 19, 1998 | 12Georgia 16, Wyoming 9 | Box score |
| Sep 19, 1998 | Iowa State 38, Ball State 0 | Box score |
| Sep 19, 1998 | 5Kansas State 48, Texas 7 | Box score |
| Sep 19, 1998 | Kentucky 31, Indiana 27 | Box score |
| Sep 19, 1998 | 7LSU 31, Auburn 19 | Box score |
| Sep 19, 1998 | Louisiana Tech 77, Louisiana 14 | Box score |
| Sep 19, 1998 | Louisville 35, Illinois 9 | Box score |
| Sep 19, 1998 | Marshall 24, South Carolina 21 | Box score |
| Sep 19, 1998 | Michigan 59, Eastern Michigan 20 | Box score |
| Sep 19, 1998 | Minnesota 41, Memphis 14 | Box score |
| Sep 19, 1998 | Ole Miss 30, Vanderbilt 6 | Box score |
| Sep 19, 1998 | Navy 38, Kent State 24 | Box score |
| Sep 19, 1998 | New Mexico State 28, New Mexico 27upset | Box score |
| Sep 19, 1998 | Northwestern 23, Rice 14upset | Box score |
| Sep 19, 1998 | 1Ohio State 35, 21Missouri 14 | Box score |
| Sep 19, 1998 | Oklahoma State 42, 25Mississippi State 23upset | Box score |
| Sep 19, 1998 | 22Oregon 58, San José State 3 | Box score |
| Sep 19, 1998 | 8Penn State 20, Pittsburgh 13 | Box score |
| Sep 19, 1998 | Purdue 35, UCF 7 | Box score |
| Sep 19, 1998 | 18USC 40, Oregon State 20 | Box score |
| Sep 19, 1998 | Stanford 37, North Carolina 34upset | Box score |
| Sep 19, 1998 | 13Syracuse 70, Rutgers 14 | Box score |
| Sep 19, 1998 | 6Tennessee 20, 2Florida 17upset | Box score |
| Sep 19, 1998 | 17Texas A&M 24, Southern Miss 6 | Box score |
| Sep 19, 1998 | Texas Tech 34, Fresno State 28 | Box score |
| Sep 19, 1998 | Toledo 35, Western Michigan 7 | Box score |
| Sep 19, 1998 | 4UCLA 42, Houston 24 | Box score |
| Sep 19, 1998 | Utah 30, Hawai’i 21 | Box score |
| Sep 19, 1998 | 10Virginia 20, Clemson 18 | Box score |
| Sep 19, 1998 | Virginia Tech 27, Miami 20 | Box score |
| Sep 19, 1998 | 9Washington 20, BYU 10 | Box score |
| Sep 19, 1998 | Washington State 24, Idaho 16 | Box score |
| Sep 19, 1998 | 19West Virginia 42, Maryland 20 | Box score |
| Sep 19, 1998 | 14Wisconsin 52, UNLV 7 | Box score |