| Sep 10, 1998 | Wake Forest 26, Navy 14 | Box score |
| Sep 12, 1998 | Air Force 52, UNLV 10 | Box score |
| Sep 12, 1998 | Akron 35, Temple 28 | Box score |
| Sep 12, 1998 | Alabama 32, Vanderbilt 7 | Box score |
| Sep 12, 1998 | 21Arizona 31, Stanford 14 | Box score |
| Sep 12, 1998 | Auburn 17, Ole Miss 0 | Box score |
| Sep 12, 1998 | Boston College 41, Rutgers 14 | Box score |
| Sep 12, 1998 | BYU 26, 14Arizona State 6upset | Box score |
| Sep 12, 1998 | 16Colorado 29, Fresno State 21 | Box score |
| Sep 12, 1998 | Colorado State 26, Nevada 14 | Box score |
| Sep 12, 1998 | Duke 44, Northwestern 10upset | Box score |
| Sep 12, 1998 | Eastern Michigan 13, Ball State 7upset | Box score |
| Sep 12, 1998 | 3Florida 42, UL Monroe 10 | Box score |
| Sep 12, 1998 | 15Georgia 17, South Carolina 3 | Box score |
| Sep 12, 1998 | Georgia Tech 42, New Mexico State 7 | Box score |
| Sep 12, 1998 | Idaho 17, San José State 12 | Box score |
| Sep 12, 1998 | Indiana 45, Western Michigan 30 | Box score |
| Sep 12, 1998 | Iowa State 27, Iowa 9upset | Box score |
| Sep 12, 1998 | 5Kansas State 73, Northern Illinois 7 | Box score |
| Sep 12, 1998 | 7LSU 42, Arkansas State 6 | Box score |
| Sep 12, 1998 | Miami 38, Cincinnati 12 | Box score |
| Sep 12, 1998 | Miami (OH) 14, Army 13 | Box score |
| Sep 12, 1998 | Michigan State 45, 10Notre Dame 23upset | Box score |
| Sep 12, 1998 | Minnesota 14, Houston 7 | Box score |
| Sep 12, 1998 | Mississippi State 14, Memphis 6 | Box score |
| Sep 12, 1998 | 25Missouri 41, Kansas 23 | Box score |
| Sep 12, 1998 | 4Nebraska 24, California 3 | Box score |
| Sep 12, 1998 | New Mexico 39, Utah State 36 | Box score |
| Sep 12, 1998 | NC State 24, 2Florida State 7upset | Box score |
| Sep 12, 1998 | 1Ohio State 49, Toledo 0 | Box score |
| Sep 12, 1998 | Oklahoma 10, TCU 9 | Box score |
| Sep 12, 1998 | 24Oregon 33, UTEP 26 | Box score |
| Sep 12, 1998 | Oregon State 27, Baylor 17 | Box score |
| Sep 12, 1998 | 9Penn State 48, Bowling Green 3 | Box score |
| Sep 12, 1998 | Purdue 21, Rice 19 | Box score |
| Sep 12, 1998 | 22USC 35, San Diego State 6 | Box score |
| Sep 12, 1998 | 19Syracuse 38, 13Michigan 28upset | Box score |
| Sep 12, 1998 | 18Texas A&M 28, Louisiana Tech 7 | Box score |
| Sep 12, 1998 | Texas Tech 30, North Texas 0 | Box score |
| Sep 12, 1998 | Tulane 31, SMU 21 | Box score |
| Sep 12, 1998 | Tulsa 35, Oklahoma State 20 | Box score |
| Sep 12, 1998 | 6UCLA 49, 23Texas 31 | Box score |
| Sep 12, 1998 | Utah 45, Louisville 22 | Box score |
| Sep 12, 1998 | 12Virginia 31, Maryland 19 | Box score |
| Sep 12, 1998 | Virginia Tech 37, Clemson 0 | Box score |
| Sep 12, 1998 | Washington State 33, Boise State 21 | Box score |
| Sep 12, 1998 | 17Wisconsin 45, Ohio 0 | Box score |