| Sep 3, 1998 | 24Arizona 27, Hawai’i 6 | Box score |
| Sep 3, 1998 | NC State 34, Ohio 31 | Box score |
| Sep 3, 1998 | 16Virginia 19, 25Auburn 0 | Box score |
| Sep 3, 1998 | Western Michigan 37, Northern Illinois 23 | Box score |
| Sep 5, 1998 | Air Force 42, Wake Forest 0 | Box score |
| Sep 5, 1998 | Alabama 38, BYU 31 | Box score |
| Sep 5, 1998 | Arkansas 38, Louisiana 17 | Box score |
| Sep 5, 1998 | Boston College 41, Georgia Tech 31upset | Box score |
| Sep 5, 1998 | California 14, Houston 10 | Box score |
| Sep 5, 1998 | UCF 64, Louisiana Tech 30 | Box score |
| Sep 5, 1998 | Colorado 42, 15Colorado State 14upset | Box score |
| Sep 5, 1998 | 19Georgia 56, Kent State 3 | Box score |
| Sep 5, 1998 | Iowa 38, Central Michigan 0 | Box score |
| Sep 5, 1998 | Kentucky 68, Louisville 34 | Box score |
| Sep 5, 1998 | Marshall 27, Akron 16 | Box score |
| Sep 5, 1998 | Miami (OH) 13, 12North Carolina 10upset | Box score |
| Sep 5, 1998 | Minnesota 17, Arkansas State 14 | Box score |
| Sep 5, 1998 | Ole Miss 30, Memphis 10 | Box score |
| Sep 5, 1998 | Mississippi State 42, Vanderbilt 0 | Box score |
| Sep 5, 1998 | Missouri 37, Bowling Green 0 | Box score |
| Sep 5, 1998 | 4Nebraska 38, UAB 7 | Box score |
| Sep 5, 1998 | Northwestern 41, UNLV 7 | Box score |
| Sep 5, 1998 | 22Notre Dame 36, 5Michigan 20upset | Box score |
| Sep 5, 1998 | 1Ohio State 34, 11West Virginia 17 | Box score |
| Sep 5, 1998 | Oklahoma 37, North Texas 9 | Box score |
| Sep 5, 1998 | Oklahoma State 38, Kansas 28 | Box score |
| Sep 5, 1998 | Oregon 48, 23Michigan State 14upset | Box score |
| Sep 5, 1998 | Oregon State 48, Nevada 6 | Box score |
| Sep 5, 1998 | 13Penn State 34, 21Southern Miss 6 | Box score |
| Sep 5, 1998 | Rice 23, SMU 17 | Box score |
| Sep 5, 1998 | San José State 35, Stanford 23upset | Box score |
| Sep 5, 1998 | South Carolina 38, Ball State 20 | Box score |
| Sep 5, 1998 | 10Tennessee 34, 17Syracuse 33 | Box score |
| Sep 5, 1998 | Texas 66, New Mexico State 36 | Box score |
| Sep 5, 1998 | TCU 31, Iowa State 21 | Box score |
| Sep 5, 1998 | Texas Tech 35, UTEP 3 | Box score |
| Sep 5, 1998 | Toledo 24, Temple 12 | Box score |
| Sep 5, 1998 | Tulane 52, Cincinnati 34 | Box score |
| Sep 5, 1998 | Utah 20, Utah State 12 | Box score |
| Sep 5, 1998 | Virginia Tech 38, East Carolina 3 | Box score |
| Sep 5, 1998 | 18Washington 42, 8Arizona State 38upset | Box score |
| Sep 5, 1998 | Washington State 20, Illinois 13 | Box score |
| Sep 5, 1998 | 20Wisconsin 26, San Diego State 14 | Box score |