| Sep 18, 1997 | Pittsburgh 21, 22Miami 17upset | Box score |
| Sep 20, 1997 | Air Force 24, 23Colorado State 0upset | Box score |
| Sep 20, 1997 | Arkansas 17, 11Alabama 16upset | Box score |
| Sep 20, 1997 | 12Auburn 31, 10LSU 28upset | Box score |
| Sep 20, 1997 | Boston College 35, Rutgers 21 | Box score |
| Sep 20, 1997 | Bowling Green 31, Akron 28 | Box score |
| Sep 20, 1997 | BYU 13, 14Arizona State 10upset | Box score |
| Sep 20, 1997 | California 40, Oklahoma 36 | Box score |
| Sep 20, 1997 | UCF 41, Idaho 10 | Box score |
| Sep 20, 1997 | Cincinnati 34, Kansas 7 | Box score |
| Sep 20, 1997 | Duke 20, Army 17upset | Box score |
| Sep 20, 1997 | 3Florida 33, 4Tennessee 20 | Box score |
| Sep 20, 1997 | 5Florida State 35, 16Clemson 28 | Box score |
| Sep 20, 1997 | 25Georgia 42, UL Monroe 3 | Box score |
| Sep 20, 1997 | Georgia Tech 28, Wake Forest 26 | Box score |
| Sep 20, 1997 | 13Iowa 63, Iowa State 20 | Box score |
| Sep 20, 1997 | Kent State 41, Eastern Michigan 38upset | Box score |
| Sep 20, 1997 | Kentucky 49, Indiana 7 | Box score |
| Sep 20, 1997 | Louisiana Tech 56, Central Michigan 28 | Box score |
| Sep 20, 1997 | 8Michigan 38, Baylor 3 | Box score |
| Sep 20, 1997 | 17Michigan State 23, Notre Dame 7 | Box score |
| Sep 20, 1997 | Minnesota 20, Memphis 17 | Box score |
| Sep 20, 1997 | Missouri 42, Tulsa 21 | Box score |
| Sep 20, 1997 | Navy 46, SMU 16 | Box score |
| Sep 20, 1997 | 7Nebraska 27, 2Washington 14upset | Box score |
| Sep 20, 1997 | UNLV 25, Hawai’i 15 | Box score |
| Sep 20, 1997 | New Mexico 25, Utah State 22 | Box score |
| Sep 20, 1997 | 6North Carolina 40, Maryland 14 | Box score |
| Sep 20, 1997 | NC State 41, Northern Illinois 14 | Box score |
| Sep 20, 1997 | North Texas 30, Texas Tech 27upset | Box score |
| Sep 20, 1997 | 9Ohio State 28, Arizona 20 | Box score |
| Sep 20, 1997 | Oregon 43, Fresno State 40 | Box score |
| Sep 20, 1997 | 1Penn State 57, Louisville 21 | Box score |
| Sep 20, 1997 | Purdue 28, Ball State 14 | Box score |
| Sep 20, 1997 | Rice 40, Northwestern 34upset | Box score |
| Sep 20, 1997 | South Carolina 26, East Carolina 0upset | Box score |
| Sep 20, 1997 | Southern Miss 35, Nevada 19 | Box score |
| Sep 20, 1997 | 21Stanford 27, Oregon State 24 | Box score |
| Sep 20, 1997 | Syracuse 30, Tulane 19 | Box score |
| Sep 20, 1997 | Texas A&M 66, Louisiana 0 | Box score |
| Sep 20, 1997 | Toledo 23, Western Michigan 13 | Box score |
| Sep 20, 1997 | Utah 56, UTEP 3 | Box score |
| Sep 20, 1997 | Vanderbilt 40, TCU 16 | Box score |
| Sep 20, 1997 | 18Virginia Tech 23, Temple 13 | Box score |
| Sep 20, 1997 | 19Washington State 35, Illinois 22 | Box score |
| Sep 20, 1997 | Wisconsin 36, San Diego State 10 | Box score |
| Sep 20, 1997 | Wyoming 30, San José State 10 | Box score |