| Sep 25, 1997 | Wake Forest 19, NC State 18 | Box score |
| Sep 27, 1997 | Air Force 24, San Diego State 18 | Box score |
| Sep 27, 1997 | 21Alabama 27, Southern Miss 13 | Box score |
| Sep 27, 1997 | UAB 42, Louisiana 7 | Box score |
| Sep 27, 1997 | 25Arizona State 13, Oregon State 10 | Box score |
| Sep 27, 1997 | Arkansas 17, Louisiana Tech 13 | Box score |
| Sep 27, 1997 | 8Auburn 41, UCF 14 | Box score |
| Sep 27, 1997 | 23BYU 19, SMU 16 | Box score |
| Sep 27, 1997 | Cincinnati 24, Boston College 6 | Box score |
| Sep 27, 1997 | 16Colorado 20, Wyoming 19 | Box score |
| Sep 27, 1997 | Duke 26, Navy 17upset | Box score |
| Sep 27, 1997 | Eastern Michigan 31, Central Michigan 24upset | Box score |
| Sep 27, 1997 | 1Florida 55, Kentucky 28 | Box score |
| Sep 27, 1997 | Georgia Tech 23, 17Clemson 20upset | Box score |
| Sep 27, 1997 | Houston 45, Minnesota 43 | Box score |
| Sep 27, 1997 | 11Iowa 38, Illinois 10 | Box score |
| Sep 27, 1997 | 18Kansas State 58, Bowling Green 0 | Box score |
| Sep 27, 1997 | 13LSU 56, Akron 0 | Box score |
| Sep 27, 1997 | Marshall 42, Ball State 16upset | Box score |
| Sep 27, 1997 | Maryland 24, Temple 21 | Box score |
| Sep 27, 1997 | Miami (OH) 38, Army 14 | Box score |
| Sep 27, 1997 | 6Michigan 21, Notre Dame 14 | Box score |
| Sep 27, 1997 | Ole Miss 15, Vanderbilt 3 | Box score |
| Sep 27, 1997 | Mississippi State 37, South Carolina 17 | Box score |
| Sep 27, 1997 | 5North Carolina 48, Virginia 20 | Box score |
| Sep 27, 1997 | Ohio 31, Western Michigan 7 | Box score |
| Sep 27, 1997 | 7Ohio State 31, Missouri 10 | Box score |
| Sep 27, 1997 | Oklahoma 35, Louisville 14 | Box score |
| Sep 27, 1997 | Oklahoma State 38, UL Monroe 7 | Box score |
| Sep 27, 1997 | Purdue 21, Northwestern 9 | Box score |
| Sep 27, 1997 | USC 27, California 17 | Box score |
| Sep 27, 1997 | 20Stanford 58, Oregon 49 | Box score |
| Sep 27, 1997 | Texas 38, Rice 31 | Box score |
| Sep 27, 1997 | 22Texas A&M 36, North Texas 10 | Box score |
| Sep 27, 1997 | UTEP 24, New Mexico State 16 | Box score |
| Sep 27, 1997 | Toledo 31, Nevada 13 | Box score |
| Sep 27, 1997 | 24UCLA 40, Arizona 27 | Box score |
| Sep 27, 1997 | 14Virginia Tech 50, Arkansas State 0 | Box score |
| Sep 27, 1997 | 15Washington State 58, Boise State 0 | Box score |
| Sep 27, 1997 | West Virginia 28, Miami 17 | Box score |
| Sep 27, 1997 | Wisconsin 27, Indiana 26 | Box score |