| Sep 11, 1997 | 15Alabama 20, Vanderbilt 0 | Box score |
| Sep 13, 1997 | Air Force 25, UNLV 24 | Box score |
| Sep 13, 1997 | Arizona 24, UAB 10 | Box score |
| Sep 13, 1997 | 24Arizona State 23, 13Miami 12upset | Box score |
| Sep 13, 1997 | 16Auburn 19, Ole Miss 9 | Box score |
| Sep 13, 1997 | Boston College 31, West Virginia 24 | Box score |
| Sep 13, 1997 | Central Michigan 44, Boise State 26 | Box score |
| Sep 13, 1997 | 19Clemson 19, NC State 17 | Box score |
| Sep 13, 1997 | 25Colorado State 35, Utah State 24 | Box score |
| Sep 13, 1997 | East Carolina 25, Wake Forest 24 | Box score |
| Sep 13, 1997 | 5Florida State 50, Maryland 7 | Box score |
| Sep 13, 1997 | Georgia 31, South Carolina 15 | Box score |
| Sep 13, 1997 | Indiana 33, Ball State 6 | Box score |
| Sep 13, 1997 | 18Iowa 54, Tulsa 16 | Box score |
| Sep 13, 1997 | Kansas 15, Missouri 7 | Box score |
| Sep 13, 1997 | 20Kansas State 23, Ohio 20 | Box score |
| Sep 13, 1997 | 10LSU 24, Mississippi State 9 | Box score |
| Sep 13, 1997 | Louisiana Tech 17, UL Monroe 16 | Box score |
| Sep 13, 1997 | Louisville 26, Illinois 14 | Box score |
| Sep 13, 1997 | Marshall 42, Kent State 17 | Box score |
| Sep 13, 1997 | Miami (OH) 49, Akron 20 | Box score |
| Sep 13, 1997 | 14Michigan 27, 8Colorado 3upset | Box score |
| Sep 13, 1997 | 21Michigan State 51, Memphis 21 | Box score |
| Sep 13, 1997 | Minnesota 53, Iowa State 29 | Box score |
| Sep 13, 1997 | Navy 36, Rutgers 7 | Box score |
| Sep 13, 1997 | 6Nebraska 38, UCF 24 | Box score |
| Sep 13, 1997 | New Mexico 38, UTEP 20 | Box score |
| Sep 13, 1997 | 7North Carolina 28, 17Stanford 17 | Box score |
| Sep 13, 1997 | Northwestern 24, Duke 20 | Box score |
| Sep 13, 1997 | 9Ohio State 44, Bowling Green 13 | Box score |
| Sep 13, 1997 | Oklahoma State 35, Fresno State 0 | Box score |
| Sep 13, 1997 | Oregon 24, Nevada 20 | Box score |
| Sep 13, 1997 | 1Penn State 52, Temple 10 | Box score |
| Sep 13, 1997 | Pittsburgh 35, Houston 24 | Box score |
| Sep 13, 1997 | Purdue 28, 12Notre Dame 17upset | Box score |
| Sep 13, 1997 | Rice 30, Tulane 24 | Box score |
| Sep 13, 1997 | SMU 31, Arkansas 9 | Box score |
| Sep 13, 1997 | Texas Tech 59, Louisiana 14 | Box score |
| Sep 13, 1997 | Toledo 38, Eastern Michigan 35 | Box score |
| Sep 13, 1997 | UCLA 66, 11Texas 3upset | Box score |
| Sep 13, 1997 | Utah 32, TCU 18 | Box score |
| Sep 13, 1997 | 22Virginia Tech 31, Syracuse 3 | Box score |
| Sep 13, 1997 | 3Washington 36, San Diego State 3 | Box score |
| Sep 13, 1997 | Washington State 28, 23USC 21upset | Box score |
| Sep 13, 1997 | Western Michigan 21, Northern Illinois 13 | Box score |
| Sep 13, 1997 | Wisconsin 56, San José State 10 | Box score |
| Sep 13, 1997 | Wyoming 35, Hawai’i 6 | Box score |