| Sep 4, 1997 | 16Auburn 28, Virginia 17 | Box score |
| Sep 4, 1997 | Oregon 16, Arizona 9 | Box score |
| Sep 5, 1997 | San Diego State 45, Navy 31 | Box score |
| Sep 6, 1997 | Air Force 41, Rice 12 | Box score |
| Sep 6, 1997 | Arkansas 28, UL Monroe 16 | Box score |
| Sep 6, 1997 | Baylor 37, Fresno State 35 | Box score |
| Sep 6, 1997 | Bowling Green 28, Miami (OH) 21 | Box score |
| Sep 6, 1997 | California 35, Houston 3 | Box score |
| Sep 6, 1997 | 8Colorado 31, 24Colorado State 21 | Box score |
| Sep 6, 1997 | 2Florida 82, Central Michigan 6 | Box score |
| Sep 6, 1997 | 5Florida State 14, 23USC 7 | Box score |
| Sep 6, 1997 | Kansas 17, TCU 10 | Box score |
| Sep 6, 1997 | 21Kansas State 47, Northern Illinois 7 | Box score |
| Sep 6, 1997 | 10LSU 55, UTEP 3 | Box score |
| Sep 6, 1997 | Marshall 35, Army 25upset | Box score |
| Sep 6, 1997 | Memphis 28, UAB 7 | Box score |
| Sep 6, 1997 | 25Michigan State 42, Western Michigan 10 | Box score |
| Sep 6, 1997 | Ole Miss 23, SMU 15 | Box score |
| Sep 6, 1997 | Mississippi State 35, Kentucky 27 | Box score |
| Sep 6, 1997 | Missouri 44, Eastern Michigan 24 | Box score |
| Sep 6, 1997 | Nevada 31, UNLV 14 | Box score |
| Sep 6, 1997 | New Mexico 61, New Mexico State 24 | Box score |
| Sep 6, 1997 | 7North Carolina 23, Indiana 6 | Box score |
| Sep 6, 1997 | NC State 45, Duke 14 | Box score |
| Sep 6, 1997 | 11Notre Dame 17, Georgia Tech 13 | Box score |
| Sep 6, 1997 | Ohio 21, Maryland 14 | Box score |
| Sep 6, 1997 | Oklahoma 36, Syracuse 34upset | Box score |
| Sep 6, 1997 | Oklahoma State 31, Louisiana 7 | Box score |
| Sep 6, 1997 | Oregon State 33, North Texas 7 | Box score |
| Sep 6, 1997 | 1Penn State 34, Pittsburgh 17 | Box score |
| Sep 6, 1997 | South Carolina 33, UCF 31 | Box score |
| Sep 6, 1997 | Southern Miss 24, Illinois 7 | Box score |
| Sep 6, 1997 | 17Stanford 28, San José State 12 | Box score |
| Sep 6, 1997 | Temple 28, Boston College 21 | Box score |
| Sep 6, 1997 | 3Tennessee 30, UCLA 24 | Box score |
| Sep 6, 1997 | 12Texas 48, Rutgers 14 | Box score |
| Sep 6, 1997 | Toledo 36, Purdue 22 | Box score |
| Sep 6, 1997 | Tulane 31, Cincinnati 17 | Box score |
| Sep 6, 1997 | Utah 27, Louisville 21 | Box score |
| Sep 6, 1997 | Wake Forest 27, 21Northwestern 20upset | Box score |
| Sep 6, 1997 | 4Washington 42, 19BYU 20 | Box score |
| Sep 6, 1997 | West Virginia 24, East Carolina 17 | Box score |
| Sep 6, 1997 | Wisconsin 28, Boise State 24 | Box score |
| Sep 6, 1997 | Wyoming 56, Iowa State 10 | Box score |