| Sep 17, 1992 | Rutgers 21, Pittsburgh 16 | Box score |
| Sep 19, 1992 | Air Force 42, Wyoming 28 | Box score |
| Sep 19, 1992 | 9Alabama 38, Arkansas 11 | Box score |
| Sep 19, 1992 | Oregon State 14, Arizona 14 | Box score |
| Sep 19, 1992 | Arizona State 19, Louisville 0 | Box score |
| Sep 19, 1992 | Auburn 30, LSU 28 | Box score |
| Sep 19, 1992 | Ball State 10, Kent State 6 | Box score |
| Sep 19, 1992 | Baylor 45, Utah State 10 | Box score |
| Sep 19, 1992 | Boston College 28, Navy 0 | Box score |
| Sep 19, 1992 | Central Michigan 24, Ohio 0 | Box score |
| Sep 19, 1992 | 11Colorado 21, Minnesota 20 | Box score |
| Sep 19, 1992 | Duke 17, Rice 12 | Box score |
| Sep 19, 1992 | East Carolina 20, South Carolina 18 | Box score |
| Sep 19, 1992 | 3Florida State 34, 16NC State 13 | Box score |
| Sep 19, 1992 | Fresno State 52, Colorado State 21 | Box score |
| Sep 19, 1992 | 19Georgia 56, Cal State Fullerton 0 | Box score |
| Sep 19, 1992 | Houston 31, Illinois 13 | Box score |
| Sep 19, 1992 | Iowa State 38, Tulane 14 | Box score |
| Sep 19, 1992 | Kansas 40, Tulsa 7 | Box score |
| Sep 19, 1992 | Kentucky 37, Indiana 25 | Box score |
| Sep 19, 1992 | Miami (OH) 17, Cincinnati 14 | Box score |
| Sep 19, 1992 | 6Michigan 35, Oklahoma State 3 | Box score |
| Sep 19, 1992 | 24Mississippi State 20, Memphis 16 | Box score |
| Sep 19, 1992 | New Mexico State 30, UTEP 24 | Box score |
| Sep 19, 1992 | North Carolina 22, Army 9 | Box score |
| Sep 19, 1992 | Northern Illinois 31, Arkansas State 0 | Box score |
| Sep 19, 1992 | 7Notre Dame 52, Michigan State 31 | Box score |
| Sep 19, 1992 | 21Ohio State 35, 8Syracuse 12upset | Box score |
| Sep 19, 1992 | Oregon 16, Texas Tech 13 | Box score |
| Sep 19, 1992 | 10Penn State 52, Eastern Michigan 7 | Box score |
| Sep 19, 1992 | San José State 38, Louisiana 13 | Box score |
| Sep 19, 1992 | USC 20, 13Oklahoma 10upset | Box score |
| Sep 19, 1992 | SMU 20, New Mexico 13 | Box score |
| Sep 19, 1992 | Southern Miss 16, Louisiana Tech 13 | Box score |
| Sep 19, 1992 | 18Stanford 35, Northwestern 24 | Box score |
| Sep 19, 1992 | 14Tennessee 31, 4Florida 14upset | Box score |
| Sep 19, 1992 | 5Texas A&M 26, Missouri 13 | Box score |
| Sep 19, 1992 | Toledo 33, Purdue 29 | Box score |
| Sep 19, 1992 | 15UCLA 17, BYU 10 | Box score |
| Sep 19, 1992 | Vanderbilt 31, 25Ole Miss 9upset | Box score |
| Sep 19, 1992 | 20Virginia 55, 22Georgia Tech 24 | Box score |
| Sep 19, 1992 | Virginia Tech 26, Temple 7 | Box score |
| Sep 19, 1992 | 2Washington 29, 12Nebraska 14 | Box score |
| Sep 19, 1992 | West Virginia 34, Maryland 33 | Box score |
| Sep 19, 1992 | Western Michigan 24, Akron 20 | Box score |
| Sep 19, 1992 | Wisconsin 39, Bowling Green 18 | Box score |