| Sep 24, 1992 | California 27, 24Kansas 23upset | Box score |
| Sep 26, 1992 | Air Force 33, New Mexico 32 | Box score |
| Sep 26, 1992 | 7Alabama 13, Louisiana Tech 0 | Box score |
| Sep 26, 1992 | Auburn 16, Southern Miss 8 | Box score |
| Sep 26, 1992 | Ball State 19, Miami (OH) 9 | Box score |
| Sep 26, 1992 | 25Boston College 14, Michigan State 0 | Box score |
| Sep 26, 1992 | Bowling Green 44, East Carolina 34 | Box score |
| Sep 26, 1992 | Central Michigan 28, Toledo 9 | Box score |
| Sep 26, 1992 | 10Colorado 28, Iowa 12 | Box score |
| Sep 26, 1992 | Colorado State 17, LSU 14upset | Box score |
| Sep 26, 1992 | 3Florida State 35, Wake Forest 7 | Box score |
| Sep 26, 1992 | 18Georgia 37, Ole Miss 11 | Box score |
| Sep 26, 1992 | Georgia Tech 20, 16Clemson 16upset | Box score |
| Sep 26, 1992 | Hawai’i 36, BYU 32 | Box score |
| Sep 26, 1992 | Indiana 20, Missouri 10 | Box score |
| Sep 26, 1992 | Kansas State 35, Temple 14 | Box score |
| Sep 26, 1992 | Kent State 17, Eastern Michigan 14upset | Box score |
| Sep 26, 1992 | Kentucky 13, South Carolina 9 | Box score |
| Sep 26, 1992 | Memphis 22, Arkansas 6 | Box score |
| Sep 26, 1992 | 1Miami 8, Arizona 7 | Box score |
| Sep 26, 1992 | 4Michigan 61, Houston 7 | Box score |
| Sep 26, 1992 | 15Nebraska 45, Arizona State 24 | Box score |
| Sep 26, 1992 | 23NC State 27, North Carolina 20 | Box score |
| Sep 26, 1992 | 6Notre Dame 48, Purdue 0 | Box score |
| Sep 26, 1992 | Oklahoma State 24, Tulsa 19 | Box score |
| Sep 26, 1992 | Oregon 59, UNLV 6 | Box score |
| Sep 26, 1992 | 9Penn State 49, Maryland 13 | Box score |
| Sep 26, 1992 | Pittsburgh 41, Minnesota 33 | Box score |
| Sep 26, 1992 | Rutgers 40, Navy 0 | Box score |
| Sep 26, 1992 | SMU 21, TCU 9 | Box score |
| Sep 26, 1992 | 19Stanford 37, San José State 13 | Box score |
| Sep 26, 1992 | 8Tennessee 40, Cincinnati 0 | Box score |
| Sep 26, 1992 | Texas Tech 36, Baylor 17 | Box score |
| Sep 26, 1992 | Tulane 34, Nevada 17 | Box score |
| Sep 26, 1992 | 11UCLA 35, 21San Diego State 7 | Box score |
| Sep 26, 1992 | Utah 42, Oregon State 9 | Box score |
| Sep 26, 1992 | Utah State 48, New Mexico State 21 | Box score |
| Sep 26, 1992 | 14Virginia 55, Duke 28 | Box score |
| Sep 26, 1992 | Washington State 39, Fresno State 37upset | Box score |
| Sep 26, 1992 | West Virginia 16, Virginia Tech 7 | Box score |
| Sep 26, 1992 | Western Michigan 19, Ohio 3 | Box score |
| Sep 26, 1992 | Wisconsin 18, Northern Illinois 17 | Box score |
| Sep 26, 1992 | Wyoming 26, Louisville 24 | Box score |