| Sep 19, 1987 | Air Force 49, San Diego State 7 | Box score |
| Sep 19, 1987 | Akron 17, Eastern Michigan 16upset | Box score |
| Sep 19, 1987 | Arizona 20, New Mexico 9 | Box score |
| Sep 19, 1987 | 15Arizona State 31, Pacific 12 | Box score |
| Sep 19, 1987 | 12Arkansas 30, Tulsa 15 | Box score |
| Sep 19, 1987 | Army 41, Kansas State 14 | Box score |
| Sep 19, 1987 | Baylor 21, UNLV 14 | Box score |
| Sep 19, 1987 | Bowling Green 24, Ball State 0 | Box score |
| Sep 19, 1987 | Cal State Fullerton 31, Long Beach State 12 | Box score |
| Sep 19, 1987 | 8Clemson 21, 18Georgia 20 | Box score |
| Sep 19, 1987 | Colorado 31, Stanford 17 | Box score |
| Sep 19, 1987 | Duke 35, Vanderbilt 31 | Box score |
| Sep 19, 1987 | Florida 23, 11Alabama 14upset | Box score |
| Sep 19, 1987 | 7Florida State 41, Memphis 24 | Box score |
| Sep 19, 1987 | Illinois 20, East Carolina 10 | Box score |
| Sep 19, 1987 | Iowa 48, Iowa State 9 | Box score |
| Sep 19, 1987 | Kent State 31, Kansas 17 | Box score |
| Sep 19, 1987 | Kentucky 34, Indiana 15 | Box score |
| Sep 19, 1987 | 4LSU 49, Rice 16 | Box score |
| Sep 19, 1987 | Purdue 22, Louisville 22 | Box score |
| Sep 19, 1987 | Maryland 25, West Virginia 20 | Box score |
| Sep 19, 1987 | 19Michigan 44, Washington State 18 | Box score |
| Sep 19, 1987 | Minnesota 32, California 23 | Box score |
| Sep 19, 1987 | Missouri 28, Northwestern 3 | Box score |
| Sep 19, 1987 | North Carolina 30, Georgia Tech 23 | Box score |
| Sep 19, 1987 | Northern Illinois 34, Western Michigan 14 | Box score |
| Sep 19, 1987 | 9Notre Dame 31, 17Michigan State 8 | Box score |
| Sep 19, 1987 | 5Ohio State 24, Oregon 14 | Box score |
| Sep 19, 1987 | Oklahoma State 35, Wyoming 29 | Box score |
| Sep 19, 1987 | Oregon State 36, San José State 34upset | Box score |
| Sep 19, 1987 | 20Penn State 41, Cincinnati 0 | Box score |
| Sep 19, 1987 | USC 23, Boston College 17 | Box score |
| Sep 19, 1987 | Southern Miss 31, Tulane 24 | Box score |
| Sep 19, 1987 | Syracuse 24, Miami (OH) 10 | Box score |
| Sep 19, 1987 | Temple 24, 16Pittsburgh 21upset | Box score |
| Sep 19, 1987 | Texas A&M 29, 10Washington 12upset | Box score |
| Sep 19, 1987 | TCU 33, BYU 12upset | Box score |
| Sep 19, 1987 | UTEP 45, Colorado State 6 | Box score |
| Sep 19, 1987 | Toledo 17, Ohio 12 | Box score |
| Sep 19, 1987 | 13UCLA 17, Fresno State 0 | Box score |
| Sep 19, 1987 | Utah 31, Wisconsin 28 | Box score |
| Sep 19, 1987 | Virginia 14, Virginia Tech 13 | Box score |
| Sep 19, 1987 | Wake Forest 21, NC State 3 | Box score |