| Sep 26, 1987 | Air Force 27, Colorado State 19 | Box score |
| Sep 26, 1987 | 17Alabama 30, Vanderbilt 23 | Box score |
| Sep 26, 1987 | 11Tennessee 20, 3Auburn 20 | Box score |
| Sep 26, 1987 | Baylor 36, Texas Tech 22 | Box score |
| Sep 26, 1987 | BYU 45, New Mexico 25 | Box score |
| Sep 26, 1987 | Cal State Fullerton 30, Utah State 11 | Box score |
| Sep 26, 1987 | Cincinnati 31, Miami (OH) 26 | Box score |
| Sep 26, 1987 | 9Clemson 33, Georgia Tech 12 | Box score |
| Sep 26, 1987 | Colorado 26, Washington State 17 | Box score |
| Sep 26, 1987 | Eastern Michigan 23, Kent State 21 | Box score |
| Sep 26, 1987 | Florida 38, Mississippi State 3 | Box score |
| Sep 26, 1987 | 6Florida State 31, Michigan State 3 | Box score |
| Sep 26, 1987 | 20Georgia 13, South Carolina 6 | Box score |
| Sep 26, 1987 | Indiana 20, Missouri 17 | Box score |
| Sep 26, 1987 | 19Iowa 38, Kansas State 13 | Box score |
| Sep 26, 1987 | 5Miami 51, 10Arkansas 7 | Box score |
| Sep 26, 1987 | 14Michigan 49, Long Beach State 0 | Box score |
| Sep 26, 1987 | Minnesota 30, Central Michigan 10 | Box score |
| Sep 26, 1987 | 2Nebraska 35, 12Arizona State 28 | Box score |
| Sep 26, 1987 | North Carolina 45, Navy 14 | Box score |
| Sep 26, 1987 | NC State 42, Maryland 14 | Box score |
| Sep 26, 1987 | Northwestern 16, Northern Illinois 16 | Box score |
| Sep 26, 1987 | 8Notre Dame 44, Purdue 20 | Box score |
| Sep 26, 1987 | 4LSU 13, 7Ohio State 13 | Box score |
| Sep 26, 1987 | 1Oklahoma 65, Tulsa 0 | Box score |
| Sep 26, 1987 | Oklahoma State 36, Louisiana 0 | Box score |
| Sep 26, 1987 | Oregon 25, San Diego State 20 | Box score |
| Sep 26, 1987 | 15Penn State 27, Boston College 17 | Box score |
| Sep 26, 1987 | Pittsburgh 6, West Virginia 3 | Box score |
| Sep 26, 1987 | Rutgers 19, Kentucky 18 | Box score |
| Sep 26, 1987 | San José State 24, Stanford 17 | Box score |
| Sep 26, 1987 | USC 31, California 14 | Box score |
| Sep 26, 1987 | Syracuse 35, Virginia Tech 21 | Box score |
| Sep 26, 1987 | Temple 23, Akron 3 | Box score |
| Sep 26, 1987 | Texas 61, Oregon State 16 | Box score |
| Sep 26, 1987 | 16Texas A&M 27, Southern Miss 14 | Box score |
| Sep 26, 1987 | UTEP 37, Hawai’i 13 | Box score |
| Sep 26, 1987 | Tulane 31, Ole Miss 24 | Box score |
| Sep 26, 1987 | 13UCLA 34, Arizona 24 | Box score |
| Sep 26, 1987 | Virginia 42, Duke 17 | Box score |
| Sep 26, 1987 | 18Washington 31, Pacific 3 | Box score |
| Sep 26, 1987 | Western Michigan 34, Bowling Green 27upset | Box score |
| Sep 26, 1987 | Wisconsin 30, Ball State 13 | Box score |
| Sep 26, 1987 | Wyoming 34, Iowa State 17 | Box score |