| Sep 29, 1979 | 2Alabama 66, Vanderbilt 3 | Box score |
| Sep 29, 1979 | Arizona 38, San José State 18 | Box score |
| Sep 29, 1979 | Arizona State 45, Oregon State 0 | Box score |
| Sep 29, 1979 | 13Arkansas 33, Tulsa 8 | Box score |
| Sep 29, 1979 | Baylor 27, Texas Tech 17 | Box score |
| Sep 29, 1979 | Bowling Green 15, Western Michigan 3upset | Box score |
| Sep 29, 1979 | BYU 31, UTEP 7 | Box score |
| Sep 29, 1979 | Cal State Fullerton 17, Pacific 7 | Box score |
| Sep 29, 1979 | Central Michigan 19, Miami (OH) 18 | Box score |
| Sep 29, 1979 | Chattanooga 27, Marshall 0 | Box score |
| Sep 29, 1979 | Cincinnati 27, Villanova 13 | Box score |
| Sep 29, 1979 | The Citadel 24, App State 23 | Box score |
| Sep 29, 1979 | Colorado 17, Indiana 16upset | Box score |
| Sep 29, 1979 | Colorado State 20, Wyoming 16 | Box score |
| Sep 29, 1979 | Cornell 36, Colgate 21 | Box score |
| Sep 29, 1979 | East Carolina 45, VMI 10 | Box score |
| Sep 29, 1979 | 12Florida State 17, Virginia Tech 10 | Box score |
| Sep 29, 1979 | Georgia Tech 33, William & Mary 7 | Box score |
| Sep 29, 1979 | 8Houston 49, West Texas 10 | Box score |
| Sep 29, 1979 | Iowa 30, Iowa State 14upset | Box score |
| Sep 29, 1979 | Kansas 37, North Texas 18upset | Box score |
| Sep 29, 1979 | Kansas State 19, Air Force 6 | Box score |
| Sep 29, 1979 | Kentucky 14, Maryland 7 | Box score |
| Sep 29, 1979 | Long Beach State 9, Northern Illinois 3 | Box score |
| Sep 29, 1979 | Louisiana 13, Arkansas State 9upset | Box score |
| Sep 29, 1979 | Louisville 31, Drake 21 | Box score |
| Sep 29, 1979 | Miami 6, Louisiana Tech 0 | Box score |
| Sep 29, 1979 | 11Michigan 14, California 10 | Box score |
| Sep 29, 1979 | Minnesota 38, Northwestern 8 | Box score |
| Sep 29, 1979 | Mississippi State 24, Florida 10 | Box score |
| Sep 29, 1979 | Navy 13, Illinois 12 | Box score |
| Sep 29, 1979 | 6Nebraska 42, 18Penn State 17 | Box score |
| Sep 29, 1979 | UNLV 48, Hawai’i 31 | Box score |
| Sep 29, 1979 | New Mexico 30, New Mexico State 16 | Box score |
| Sep 29, 1979 | North Carolina 41, Army 3 | Box score |
| Sep 29, 1979 | 16NC State 17, Wake Forest 14 | Box score |
| Sep 29, 1979 | 15Notre Dame 27, 7Michigan State 3upset | Box score |
| Sep 29, 1979 | Ohio 43, Kent State 13 | Box score |
| Sep 29, 1979 | 14Ohio State 17, 17UCLA 13 | Box score |
| Sep 29, 1979 | 3Oklahoma 63, Rice 21 | Box score |
| Sep 29, 1979 | Pittsburgh 10, Temple 9 | Box score |
| Sep 29, 1979 | 10Purdue 13, Oregon 7 | Box score |
| Sep 29, 1979 | Rutgers 38, Princeton 14 | Box score |
| Sep 29, 1979 | San Diego State 24, Wisconsin 17 | Box score |
| Sep 29, 1979 | South Carolina 27, Georgia 20 | Box score |
| Sep 29, 1979 | 1USC 17, 20LSU 12 | Box score |
| Sep 29, 1979 | Southern Miss 38, Ole Miss 8 | Box score |
| Sep 29, 1979 | Stanford 33, Boston College 14 | Box score |
| Sep 29, 1979 | Syracuse 52, Washington State 25 | Box score |
| Sep 29, 1979 | Tennessee 35, Auburn 17 | Box score |
| Sep 29, 1979 | 4Texas 21, 5Missouri 0 | Box score |
| Sep 29, 1979 | Texas A&M 17, Memphis 7 | Box score |
| Sep 29, 1979 | Texas–Arlington 21, TCU 14 | Box score |
| Sep 29, 1979 | Toledo 37, Eastern Michigan 7 | Box score |
| Sep 29, 1979 | Tulane 24, 19SMU 17upset | Box score |
| Sep 29, 1979 | Utah State 47, Utah 21 | Box score |
| Sep 29, 1979 | Virginia 30, Duke 12 | Box score |
| Sep 29, 1979 | 9Washington 49, Fresno State 14 | Box score |
| Sep 29, 1979 | West Virginia 20, Richmond 18 | Box score |