| Sep 17, 1977 | Arizona State 35, Northwestern 3 | Box score |
| Sep 17, 1977 | Arkansas 28, 15Oklahoma State 6upset | Box score |
| Sep 17, 1977 | Army 27, VMI 14 | Box score |
| Sep 17, 1977 | Baylor 21, Kentucky 6 | Box score |
| Sep 17, 1977 | California 24, Air Force 14 | Box score |
| Sep 17, 1977 | Central Michigan 28, Illinois State 7 | Box score |
| Sep 17, 1977 | Chattanooga 14, App State 7upset | Box score |
| Sep 17, 1977 | Louisville 17, Cincinnati 17 | Box score |
| Sep 17, 1977 | The Citadel 20, Western Carolina 0 | Box score |
| Sep 17, 1977 | Clemson 7, 17Georgia 6upset | Box score |
| Sep 17, 1977 | 12Colorado 42, Kent State 0 | Box score |
| Sep 17, 1977 | Colorado State 20, Hawai’i 16 | Box score |
| Sep 17, 1977 | Dartmouth 14, Princeton 11 | Box score |
| Sep 17, 1977 | East Carolina 22, Toledo 9 | Box score |
| Sep 17, 1977 | Eastern Michigan 16, Bowling Green 6upset | Box score |
| Sep 17, 1977 | 19Florida 48, Rice 3 | Box score |
| Sep 17, 1977 | Florida State 18, Kansas State 10 | Box score |
| Sep 17, 1977 | Georgia Tech 10, Miami 6 | Box score |
| Sep 17, 1977 | Harvard 21, Columbia 7 | Box score |
| Sep 17, 1977 | Illinois 11, Missouri 7 | Box score |
| Sep 17, 1977 | Indiana 24, LSU 21 | Box score |
| Sep 17, 1977 | Indiana State 14, Southern Illinois 9upset | Box score |
| Sep 17, 1977 | Iowa 12, Iowa State 10 | Box score |
| Sep 17, 1977 | Long Beach State 50, Cal State Fullerton 31 | Box score |
| Sep 17, 1977 | Louisiana 10, Lamar 6 | Box score |
| Sep 17, 1977 | McNeese 20, West Texas 8 | Box score |
| Sep 17, 1977 | Memphis 31, Utah State 26 | Box score |
| Sep 17, 1977 | 1Michigan 21, Duke 9 | Box score |
| Sep 17, 1977 | Ole Miss 20, 3Notre Dame 13upset | Box score |
| Sep 17, 1977 | Nebraska 31, 4Alabama 24upset | Box score |
| Sep 17, 1977 | New Mexico State 24, Wichita State 12 | Box score |
| Sep 17, 1977 | North Carolina 31, Richmond 0 | Box score |
| Sep 17, 1977 | NC State 38, Syracuse 0 | Box score |
| Sep 17, 1977 | North Texas 24, SMU 13 | Box score |
| Sep 17, 1977 | 6Ohio State 38, Minnesota 7 | Box score |
| Sep 17, 1977 | 5Oklahoma 62, Utah 24 | Box score |
| Sep 17, 1977 | Oregon 29, TCU 24 | Box score |
| Sep 17, 1977 | Pacific 31, Idaho 21 | Box score |
| Sep 17, 1977 | 10Penn State 31, 9Houston 14upset | Box score |
| Sep 17, 1977 | Pennsylvania 17, Cornell 7 | Box score |
| Sep 17, 1977 | 16Pittsburgh 28, William & Mary 6 | Box score |
| Sep 17, 1977 | Purdue 44, Ohio 7 | Box score |
| Sep 17, 1977 | San Diego State 21, Arizona 14 | Box score |
| Sep 17, 1977 | South Carolina 42, Miami (OH) 19 | Box score |
| Sep 17, 1977 | 2USC 17, Oregon State 10 | Box score |
| Sep 17, 1977 | Southern Miss 24, Auburn 13upset | Box score |
| Sep 17, 1977 | Stanford 21, Tulane 17 | Box score |
| Sep 17, 1977 | Temple 42, Drake 0 | Box score |
| Sep 17, 1977 | Tennessee 24, Boston College 18 | Box score |
| Sep 17, 1977 | 18Texas 68, Virginia 0 | Box score |
| Sep 17, 1977 | 7Texas A&M 27, Virginia Tech 6 | Box score |
| Sep 17, 1977 | 8Texas Tech 49, New Mexico 14 | Box score |
| Sep 17, 1977 | Texas–Arlington 17, Western Michigan 10 | Box score |
| Sep 17, 1977 | Tulsa 37, UL Monroe 35 | Box score |
| Sep 17, 1977 | 14UCLA 17, Kansas 7 | Box score |
| Sep 17, 1977 | Vanderbilt 3, Wake Forest 0upset | Box score |
| Sep 17, 1977 | Villanova 38, Ball State 16 | Box score |
| Sep 17, 1977 | Washington 24, San José State 3 | Box score |
| Sep 17, 1977 | Washington State 23, Michigan State 21 | Box score |
| Sep 17, 1977 | West Virginia 24, 11Maryland 16upset | Box score |
| Sep 17, 1977 | Wisconsin 14, Northern Illinois 3 | Box score |
| Sep 17, 1977 | Wyoming 27, UTEP 17 | Box score |
| Sep 17, 1977 | Yale 10, Brown 9 | Box score |