| Sep 10, 1977 | Wyoming 0, Air Force 0 | Box score |
| Sep 10, 1977 | 6Alabama 34, Ole Miss 13 | Box score |
| Sep 10, 1977 | Arkansas 53, New Mexico State 10 | Box score |
| Sep 10, 1977 | Arkansas State 31, Drake 29 | Box score |
| Sep 10, 1977 | Auburn 21, Arizona 10 | Box score |
| Sep 10, 1977 | Ball State 43, Toledo 3 | Box score |
| Sep 10, 1977 | BYU 39, Kansas State 0 | Box score |
| Sep 10, 1977 | California 27, Tennessee 17 | Box score |
| Sep 10, 1977 | Central Michigan 9, Eastern Michigan 3 | Box score |
| Sep 10, 1977 | Colgate 23, Rutgers 0 | Box score |
| Sep 10, 1977 | 12Colorado 27, Stanford 21 | Box score |
| Sep 10, 1977 | Colorado State 20, Pacific 3 | Box score |
| Sep 10, 1977 | East Carolina 17, Duke 16 | Box score |
| Sep 10, 1977 | Florida State 35, Southern Miss 6 | Box score |
| Sep 10, 1977 | 19Georgia 27, Oregon 16 | Box score |
| Sep 10, 1977 | Grambling 42, Alcorn State 17upset | Box score |
| Sep 10, 1977 | Iowa 24, Northwestern 0 | Box score |
| Sep 10, 1977 | Iowa State 35, Wichita State 9 | Box score |
| Sep 10, 1977 | Kent State 33, Illinois State 14 | Box score |
| Sep 10, 1977 | Kentucky 10, North Carolina 7 | Box score |
| Sep 10, 1977 | Lamar 21, UL Monroe 7 | Box score |
| Sep 10, 1977 | Louisiana 34, Fresno State 13 | Box score |
| Sep 10, 1977 | Louisville 38, Northern Illinois 0 | Box score |
| Sep 10, 1977 | 10Maryland 21, Clemson 14 | Box score |
| Sep 10, 1977 | McNeese 25, Indiana State 7 | Box score |
| Sep 10, 1977 | Memphis 27, Tulane 9 | Box score |
| Sep 10, 1977 | 2Michigan 37, Illinois 9 | Box score |
| Sep 10, 1977 | Michigan State 19, Purdue 14 | Box score |
| Sep 10, 1977 | Minnesota 10, Western Michigan 0 | Box score |
| Sep 10, 1977 | 16Mississippi State 27, Washington 18 | Box score |
| Sep 10, 1977 | Navy 21, The Citadel 2 | Box score |
| Sep 10, 1977 | New Mexico 35, Hawai’i 26 | Box score |
| Sep 10, 1977 | NC State 14, Virginia 0 | Box score |
| Sep 10, 1977 | North Texas 41, UTEP 10 | Box score |
| Sep 10, 1977 | 3Notre Dame 19, 7Pittsburgh 9 | Box score |
| Sep 10, 1977 | Ohio 49, Marshall 27 | Box score |
| Sep 10, 1977 | 5Ohio State 10, Miami 0 | Box score |
| Sep 10, 1977 | 1Oklahoma 25, Vanderbilt 23 | Box score |
| Sep 10, 1977 | 20Oklahoma State 34, Tulsa 17 | Box score |
| Sep 10, 1977 | Oregon State 24, Syracuse 12 | Box score |
| Sep 10, 1977 | Rice 31, Idaho 10 | Box score |
| Sep 10, 1977 | San Diego State 34, Cal State Fullerton 17 | Box score |
| Sep 10, 1977 | South Carolina 17, Georgia Tech 0 | Box score |
| Sep 10, 1977 | 4USC 27, Missouri 10 | Box score |
| Sep 10, 1977 | Southern Illinois 24, Temple 20upset | Box score |
| Sep 10, 1977 | SMU 45, TCU 21 | Box score |
| Sep 10, 1977 | Tennessee State 17, Jackson State 7upset | Box score |
| Sep 10, 1977 | Texas 44, Boston College 0 | Box score |
| Sep 10, 1977 | 9Texas A&M 28, Kansas 14 | Box score |
| Sep 10, 1977 | Southern 14, Texas Southern 14 | Box score |
| Sep 10, 1977 | 8Texas Tech 17, Baylor 7 | Box score |
| Sep 10, 1977 | Utah State 22, San José State 10 | Box score |
| Sep 10, 1977 | VMI 23, William & Mary 13 | Box score |
| Sep 10, 1977 | Wake Forest 24, Furman 13 | Box score |
| Sep 10, 1977 | Washington State 19, 15Nebraska 10upset | Box score |
| Sep 10, 1977 | West Virginia 36, Richmond 0 | Box score |
| Sep 10, 1977 | Wisconsin 30, Indiana 14 | Box score |
| Sep 12, 1977 | 14Houston 17, 11UCLA 13upset | Box score |