| Sep 14, 1974 | Air Force 37, Idaho 0 | Box score |
| Sep 14, 1974 | 3Alabama 21, 14Maryland 16 | Box score |
| Sep 14, 1974 | 17Arizona 17, San Diego State 10 | Box score |
| Sep 14, 1974 | 20Arkansas 22, 5USC 7upset | Box score |
| Sep 14, 1974 | Auburn 16, Louisville 3 | Box score |
| Sep 14, 1974 | East Carolina 24, Bowling Green 6 | Box score |
| Sep 14, 1974 | Florida 21, California 17 | Box score |
| Sep 14, 1974 | Georgia 48, Oregon State 35 | Box score |
| Sep 14, 1974 | Georgia Tech 35, South Carolina 20 | Box score |
| Sep 14, 1974 | Hawai’i 15, BYU 13upset | Box score |
| Sep 14, 1974 | 19Houston 21, Rice 0 | Box score |
| Sep 14, 1974 | Illinois 16, Indiana 0 | Box score |
| Sep 14, 1974 | Kansas 14, Washington State 7 | Box score |
| Sep 14, 1974 | Kansas State 31, Tulsa 14 | Box score |
| Sep 14, 1974 | Kent State 20, Syracuse 14 | Box score |
| Sep 14, 1974 | Kentucky 38, Virginia Tech 7 | Box score |
| Sep 14, 1974 | 9LSU 42, Colorado 14 | Box score |
| Sep 14, 1974 | 6Michigan 24, Iowa 7 | Box score |
| Sep 14, 1974 | Michigan State 41, Northwestern 7 | Box score |
| Sep 14, 1974 | Ole Miss 10, 18Missouri 0upset | Box score |
| Sep 14, 1974 | Navy 35, Virginia 28 | Box score |
| Sep 14, 1974 | 7Nebraska 61, Oregon 7 | Box score |
| Sep 14, 1974 | New Mexico 32, Colorado State 23 | Box score |
| Sep 14, 1974 | New Mexico State 28, Southern Illinois 9 | Box score |
| Sep 14, 1974 | North Carolina 42, Ohio 7 | Box score |
| Sep 14, 1974 | 16NC State 35, Duke 21 | Box score |
| Sep 14, 1974 | Northern Illinois 16, Long Beach State 14 | Box score |
| Sep 14, 1974 | 4Ohio State 34, Minnesota 19 | Box score |
| Sep 14, 1974 | 1Oklahoma 28, Baylor 11 | Box score |
| Sep 14, 1974 | Oklahoma State 59, Wichita State 0 | Box score |
| Sep 14, 1974 | Pacific 17, UTEP 14 | Box score |
| Sep 14, 1974 | 8Penn State 24, 20Stanford 20 | Box score |
| Sep 14, 1974 | 13Pittsburgh 9, Florida State 6 | Box score |
| Sep 14, 1974 | Richmond 29, West Virginia 25 | Box score |
| Sep 14, 1974 | San José State 28, Fresno State 7 | Box score |
| Sep 14, 1974 | SMU 7, North Texas 6 | Box score |
| Sep 14, 1974 | Southern Miss 6, Memphis 0 | Box score |
| Sep 14, 1974 | Tampa 47, Toledo 13 | Box score |
| Sep 14, 1974 | 10Texas 42, Boston College 19 | Box score |
| Sep 14, 1974 | Texas A&M 24, Clemson 0 | Box score |
| Sep 14, 1974 | TCU 12, Texas–Arlington 3 | Box score |
| Sep 14, 1974 | Texas Tech 24, Iowa State 3 | Box score |
| Sep 14, 1974 | Tulane 17, Louisiana 16 | Box score |
| Sep 14, 1974 | Utah State 17, Wyoming 7 | Box score |
| Sep 14, 1974 | VMI 7, Furman 0 | Box score |
| Sep 14, 1974 | Washington 21, Cincinnati 17 | Box score |
| Sep 14, 1974 | West Texas 37, Drake 17 | Box score |
| Sep 14, 1974 | William & Mary 17, Wake Forest 6 | Box score |
| Sep 14, 1974 | Wisconsin 28, Purdue 14 | Box score |