| Sep 29, 1972 | 15UCLA 65, Oregon 20 | Box score |
| Sep 30, 1972 | Air Force 68, Davidson 6 | Box score |
| Sep 30, 1972 | 6Alabama 48, Vanderbilt 21 | Box score |
| Sep 30, 1972 | Arkansas 21, Tulsa 20 | Box score |
| Sep 30, 1972 | Army 24, Texas A&M 14 | Box score |
| Sep 30, 1972 | Auburn 10, 4Tennessee 6upset | Box score |
| Sep 30, 1972 | Western Michigan 13, Bowling Green 13 | Box score |
| Sep 30, 1972 | Cincinnati 14, Villanova 7 | Box score |
| Sep 30, 1972 | Cornell 37, Colgate 7 | Box score |
| Sep 30, 1972 | Drake 54, North Texas 8 | Box score |
| Sep 30, 1972 | Duke 37, Virginia 13 | Box score |
| Sep 30, 1972 | Florida 28, Mississippi State 13 | Box score |
| Sep 30, 1972 | 16Florida State 44, Kansas 22 | Box score |
| Sep 30, 1972 | Fresno State 23, San José State 21 | Box score |
| Sep 30, 1972 | Georgia 28, NC State 22 | Box score |
| Sep 30, 1972 | Indiana 35, Kentucky 34 | Box score |
| Sep 30, 1972 | Iowa State 31, New Mexico 0 | Box score |
| Sep 30, 1972 | Kansas State 31, Tampa 7 | Box score |
| Sep 30, 1972 | 9LSU 27, Wisconsin 7 | Box score |
| Sep 30, 1972 | Louisville 28, Dayton 11 | Box score |
| Sep 30, 1972 | Miami (OH) 25, Xavier 7 | Box score |
| Sep 30, 1972 | 8Michigan 41, 18Tulane 7 | Box score |
| Sep 30, 1972 | 17Ole Miss 13, Southern Miss 9 | Box score |
| Sep 30, 1972 | Missouri 34, California 27 | Box score |
| Sep 30, 1972 | Navy 27, Boston College 20 | Box score |
| Sep 30, 1972 | 7Nebraska 49, Minnesota 0 | Box score |
| Sep 30, 1972 | Northern Illinois 24, Marshall 7 | Box score |
| Sep 30, 1972 | Northwestern 27, Pittsburgh 22 | Box score |
| Sep 30, 1972 | 10Notre Dame 35, Purdue 14 | Box score |
| Sep 30, 1972 | Ohio 38, Toledo 22upset | Box score |
| Sep 30, 1972 | 5Ohio State 29, North Carolina 14 | Box score |
| Sep 30, 1972 | 2Oklahoma 52, Clemson 3 | Box score |
| Sep 30, 1972 | Oklahoma State 31, 3Colorado 6upset | Box score |
| Sep 30, 1972 | Oregon State 29, BYU 3 | Box score |
| Sep 30, 1972 | 13Penn State 14, Iowa 10 | Box score |
| Sep 30, 1972 | Princeton 7, Rutgers 6 | Box score |
| Sep 30, 1972 | Georgia Tech 36, Rice 36 | Box score |
| Sep 30, 1972 | Richmond 34, VMI 15 | Box score |
| Sep 30, 1972 | San Diego State 14, Kent State 0 | Box score |
| Sep 30, 1972 | South Carolina 34, Memphis 7 | Box score |
| Sep 30, 1972 | 1USC 51, Michigan State 6 | Box score |
| Sep 30, 1972 | 19Stanford 41, 20West Virginia 35 | Box score |
| Sep 30, 1972 | Syracuse 16, Maryland 12 | Box score |
| Sep 30, 1972 | Temple 15, Holy Cross 7 | Box score |
| Sep 30, 1972 | 12Texas 25, Texas Tech 20 | Box score |
| Sep 30, 1972 | TCU 38, Texas–Arlington 14 | Box score |
| Sep 30, 1972 | UTEP 21, New Mexico State 20 | Box score |
| Sep 30, 1972 | Utah 44, Washington State 25upset | Box score |
| Sep 30, 1972 | Utah State 21, Colorado State 0 | Box score |
| Sep 30, 1972 | Virginia Tech 13, SMU 10 | Box score |
| Sep 30, 1972 | 14Washington 31, Illinois 11 | Box score |
| Sep 30, 1972 | William & Mary 31, The Citadel 12 | Box score |
| Sep 30, 1972 | Wyoming 45, 11Arizona State 43upset | Box score |