1950: Week 2
52 games. Winners are listed first; numbers before names are AP ranks going in.
FBS vs. FBS
Everyone else
| Sep 20, 1950 | Bradley 33, Ripon 0 | Box score |
| Sep 22, 1950 | Detroit Mercy 40, Hillsdale 0 | Box score |
| Sep 22, 1950 | Loyola Marymount 50, Pepperdine 14 | Box score |
| Sep 22, 1950 | Ole Miss 39, Memphis 7 | Box score |
| Sep 22, 1950 | Wofford 19, Auburn 14upset | Box score |
| Sep 23, 1950 | Clemson 55, Presbyterian 0 | Box score |
| Sep 23, 1950 | Drake 47, Emporia State 6 | Box score |
| Sep 23, 1950 | Marquette 57, North Dakota State 0 | Box score |
| Sep 23, 1950 | Mississippi State 67, Arkansas State 0 | Box score |
| Sep 23, 1950 | Montana 52, Eastern Washington 0 | Box score |
| Sep 23, 1950 | New Mexico 78, Northern Arizona 0 | Box score |
| Sep 23, 1950 | Richmond 20, Randolph Macon 6 | Box score |
| Sep 23, 1950 | St. Bonaventure 29, Houston 14 | Box score |
| Sep 23, 1950 | Temple 32, Albright 6 | Box score |
| Sep 23, 1950 | Tennessee 56, Southern Miss 0 | Box score |
| Sep 23, 1950 | Vanderbilt 47, Middle Tennessee 0 | Box score |
| Sep 23, 1950 | West Virginia 38, Western Reserve 13 | Box score |
| Sep 23, 1950 | Yale 25, UConn 0 | Box score |