| Oct 8, 2015 | Eastern Kentucky 48, Tennessee Tech 17 | Box score |
| Oct 8, 2015 | Bethune-Cookman 17, South Carolina State 14 | Box score |
| Oct 10, 2015 | Charleston Southern 37, Monmouth 7 | Box score |
| Oct 10, 2015 | Rhode Island 20, Delaware 0upset | Box score |
| Oct 10, 2015 | William & Mary 38, Villanova 16 | Box score |
| Oct 10, 2015 | Harvard 40, Cornell 3 | Box score |
| Oct 10, 2015 | Sacred Heart 26, Robert Morris 13 | Box score |
| Oct 10, 2015 | Kennesaw State 56, Point University 17 | Box score |
| Oct 10, 2015 | Chattanooga 31, Furman 3 | Box score |
| Oct 10, 2015 | Lehigh 21, Bucknell 10upset | Box score |
| Oct 10, 2015 | Princeton 44, Colgate 20 | Box score |
| Oct 10, 2015 | Fordham 48, Pennsylvania 45 | Box score |
| Oct 10, 2015 | Central Connecticut 35, Bryant 33upset | Box score |
| Oct 10, 2015 | Duquesne 53, Alderson-Broaddus 18 | Box score |
| Oct 10, 2015 | Davidson 14, Kentucky Wesleyan 7 | Box score |
| Oct 10, 2015 | Dayton 13, San Diego 12 | Box score |
| Oct 10, 2015 | Morehead State 34, Butler 21 | Box score |
| Oct 10, 2015 | Brown 25, Holy Cross 24 | Box score |
| Oct 10, 2015 | Samford 49, VMI 13 | Box score |
| Oct 10, 2015 | Dartmouth 35, Yale 3 | Box score |
| Oct 10, 2015 | Idaho State 37, North Dakota 31upset | Box score |
| Oct 10, 2015 | Coastal Carolina 24, Presbyterian 17 | Box score |
| Oct 10, 2015 | North Dakota State 31, Northern Iowa 28 | Box score |
| Oct 10, 2015 | Eastern Illinois 33, Southeast Missouri State 28 | Box score |
| Oct 10, 2015 | The Citadel 39, Wofford 12 | Box score |
| Oct 10, 2015 | Georgetown 38, Lafayette 7 | Box score |
| Oct 10, 2015 | Hampton 21, Delaware State 7 | Box score |
| Oct 10, 2015 | North Carolina A&T 27, Norfolk State 3 | Box score |
| Oct 10, 2015 | Drake 34, Valparaiso 7 | Box score |
| Oct 10, 2015 | James Madison 51, Towson 30 | Box score |
| Oct 10, 2015 | Prairie View A&M 45, Mississippi Valley State 6 | Box score |
| Oct 10, 2015 | Maine 39, UAlbany 7 | Box score |
| Oct 10, 2015 | Richmond 27, Elon 14 | Box score |
| Oct 10, 2015 | UT Martin 28, Tennessee State 14 | Box score |
| Oct 10, 2015 | Western Carolina 24, Mercer 21 | Box score |
| Oct 10, 2015 | Central Arkansas 43, Houston Christian 7 | Box score |
| Oct 10, 2015 | Weber State 24, Montana 21upset | Box score |
| Oct 10, 2015 | Western Illinois 40, South Dakota 21 | Box score |
| Oct 10, 2015 | Murray State 34, Austin Peay 18 | Box score |
| Oct 10, 2015 | Grambling 37, Alabama A&M 14 | Box score |
| Oct 10, 2015 | Morgan State 42, Savannah State 3 | Box score |
| Oct 10, 2015 | Stephen F. Austin 28, Nicholls 24 | Box score |
| Oct 10, 2015 | Eastern Washington 42, Cal Poly 41 | Box score |
| Oct 10, 2015 | Portland State 66, North Texas 7 | Box score |
| Oct 10, 2015 | North Carolina Central 27, Florida A&M 24 | Box score |
| Oct 10, 2015 | Columbia 26, Wagner 3 | Box score |
| Oct 10, 2015 | Marist 13, Campbell 10 | Box score |
| Oct 10, 2015 | Jacksonville 41, Stetson 14 | Box score |
| Oct 10, 2015 | UC Davis 38, Northern Arizona 24upset | Box score |
| Oct 10, 2015 | Gardner-Webb 34, Liberty 20upset | Box score |
| Oct 10, 2015 | Illinois State 31, Youngstown State 29 | Box score |
| Oct 10, 2015 | Southern Illinois 73, Missouri State 26 | Box score |
| Oct 10, 2015 | South Dakota State 24, Indiana State 7 | Box score |
| Oct 10, 2015 | Southern 45, Alabama State 34 | Box score |
| Oct 10, 2015 | McNeese 21, SE Louisiana 7 | Box score |
| Oct 10, 2015 | Sam Houston 59, Incarnate Word 7 | Box score |
| Oct 10, 2015 | Montana State 35, Sacramento State 13 | Box score |
| Oct 10, 2015 | Lamar 44, Abilene Christian 28 | Box score |