| Sep 9, 1993 | 6Syracuse 41, East Carolina 22 | Box score |
| Sep 9, 1993 | Temple 31, Eastern Michigan 28 | Box score |
| Sep 11, 1993 | Akron 42, Kent State 7 | Box score |
| Sep 11, 1993 | 2Alabama 17, Vanderbilt 6 | Box score |
| Sep 11, 1993 | 13Arizona 16, Pacific 13 | Box score |
| Sep 11, 1993 | Arkansas 18, 19South Carolina 17upset | Box score |
| Sep 11, 1993 | Bowling Green 21, Cincinnati 7 | Box score |
| Sep 11, 1993 | 20BYU 41, Hawai’i 38 | Box score |
| Sep 11, 1993 | California 45, San Diego State 25 | Box score |
| Sep 11, 1993 | Central Michigan 38, Ohio 0 | Box score |
| Sep 11, 1993 | 10Colorado 45, 24Baylor 21 | Box score |
| Sep 11, 1993 | Colorado State 8, Air Force 5 | Box score |
| Sep 11, 1993 | 7Florida 24, Kentucky 20 | Box score |
| Sep 11, 1993 | 1Florida State 57, 21Clemson 0 | Box score |
| Sep 11, 1993 | Fresno State 48, Oregon State 30 | Box score |
| Sep 11, 1993 | Indiana 28, Northern Illinois 10 | Box score |
| Sep 11, 1993 | Iowa 31, Iowa State 28 | Box score |
| Sep 11, 1993 | LSU 18, Mississippi State 16upset | Box score |
| Sep 11, 1993 | Louisville 54, Memphis 28upset | Box score |
| Sep 11, 1993 | Miami (OH) 29, Louisiana 28 | Box score |
| Sep 11, 1993 | Michigan State 31, Kansas 14 | Box score |
| Sep 11, 1993 | Missouri 31, Illinois 3 | Box score |
| Sep 11, 1993 | 9Nebraska 50, Texas Tech 27 | Box score |
| Sep 11, 1993 | New Mexico State 22, Arkansas State 19 | Box score |
| Sep 11, 1993 | 14North Carolina 59, Maryland 42 | Box score |
| Sep 11, 1993 | 18NC State 34, Wake Forest 16 | Box score |
| Sep 11, 1993 | 11Notre Dame 27, 3Michigan 23upset | Box score |
| Sep 11, 1993 | 16Ohio State 21, 12Washington 12upset | Box score |
| Sep 11, 1993 | 17Oklahoma 44, 5Texas A&M 14upset | Box score |
| Sep 11, 1993 | 15Penn State 21, USC 20 | Box score |
| Sep 11, 1993 | Purdue 28, Western Michigan 13 | Box score |
| Sep 11, 1993 | Rice 34, Tulane 0 | Box score |
| Sep 11, 1993 | Rutgers 39, Duke 38 | Box score |
| Sep 11, 1993 | 23Stanford 31, San José State 28 | Box score |
| Sep 11, 1993 | 8Tennessee 38, 22Georgia 6 | Box score |
| Sep 11, 1993 | TCU 35, New Mexico 34 | Box score |
| Sep 11, 1993 | UTEP 41, UNLV 24 | Box score |
| Sep 11, 1993 | Tulsa 38, Houston 24 | Box score |
| Sep 11, 1993 | Utah 31, Utah State 29 | Box score |
| Sep 11, 1993 | Virginia 38, Navy 0 | Box score |
| Sep 11, 1993 | Virginia Tech 63, Pittsburgh 21 | Box score |
| Sep 11, 1993 | Wisconsin 24, SMU 16 | Box score |