| Sep 2, 1993 | Akron 23, Central Michigan 13 | Box score |
| Sep 2, 1993 | Auburn 16, Ole Miss 12 | Box score |
| Sep 2, 1993 | Iowa State 54, Northern Illinois 10 | Box score |
| Sep 4, 1993 | 2Alabama 31, Tulane 17 | Box score |
| Sep 4, 1993 | 13Arizona 24, UTEP 6 | Box score |
| Sep 4, 1993 | Arizona State 38, Utah 0 | Box score |
| Sep 4, 1993 | Arkansas 10, SMU 6 | Box score |
| Sep 4, 1993 | Baylor 42, 25Fresno State 39upset | Box score |
| Sep 4, 1993 | 19BYU 34, New Mexico 31 | Box score |
| Sep 4, 1993 | California 27, UCLA 25 | Box score |
| Sep 4, 1993 | 22Clemson 24, UNLV 14 | Box score |
| Sep 4, 1993 | 11Colorado 36, Texas 14 | Box score |
| Sep 4, 1993 | 8Florida 44, Arkansas State 6 | Box score |
| Sep 4, 1993 | 1Florida State 45, Duke 7 | Box score |
| Sep 4, 1993 | Indiana 27, Toledo 0 | Box score |
| Sep 4, 1993 | Iowa 26, Tulsa 25 | Box score |
| Sep 4, 1993 | Kansas State 34, New Mexico State 10 | Box score |
| Sep 4, 1993 | Kentucky 35, Kent State 0 | Box score |
| Sep 4, 1993 | Louisville 31, San José State 24 | Box score |
| Sep 4, 1993 | Memphis 45, 23Mississippi State 35upset | Box score |
| Sep 4, 1993 | 3Miami 23, 20Boston College 7 | Box score |
| Sep 4, 1993 | 3Michigan 41, Washington State 14 | Box score |
| Sep 4, 1993 | 16North Carolina 44, Ohio 3 | Box score |
| Sep 4, 1993 | 24NC State 20, Purdue 7 | Box score |
| Sep 4, 1993 | 7Notre Dame 27, Northwestern 12 | Box score |
| Sep 4, 1993 | 18Ohio State 34, Rice 7 | Box score |
| Sep 4, 1993 | 21Oklahoma 35, TCU 3 | Box score |
| Sep 4, 1993 | Oregon 23, Colorado State 9 | Box score |
| Sep 4, 1993 | Oregon State 27, Wyoming 16upset | Box score |
| Sep 4, 1993 | 17Penn State 38, Minnesota 20 | Box score |
| Sep 4, 1993 | Pittsburgh 14, Southern Miss 10upset | Box score |
| Sep 4, 1993 | South Carolina 23, 14Georgia 21upset | Box score |
| Sep 4, 1993 | USC 49, Houston 7 | Box score |
| Sep 4, 1993 | 6Syracuse 35, Ball State 12 | Box score |
| Sep 4, 1993 | 10Tennessee 50, Louisiana Tech 0 | Box score |
| Sep 4, 1993 | 5Texas A&M 24, LSU 0 | Box score |
| Sep 4, 1993 | Texas Tech 55, Pacific 7 | Box score |
| Sep 4, 1993 | Utah State 34, Louisiana 13 | Box score |
| Sep 4, 1993 | Vanderbilt 27, Wake Forest 12upset | Box score |
| Sep 4, 1993 | Virginia 43, Maryland 29 | Box score |
| Sep 4, 1993 | Virginia Tech 33, Bowling Green 16 | Box score |
| Sep 4, 1993 | 12Washington 31, 15Stanford 14 | Box score |
| Sep 4, 1993 | West Virginia 48, Eastern Michigan 6 | Box score |
| Sep 4, 1993 | Wisconsin 35, Nevada 17 | Box score |