1985: Week 2
43 games. Five ranked teams lost. Five games matched two ranked teams. Winners are listed first; numbers before names are AP ranks going in.
The week in review
Ranked against ranked
| Sep 7, 1985 | 6USC 20, 11Illinois 10 | Box score |
| Sep 7, 1985 | 19Penn State 20, 7Maryland 18upset | Box score |
| Sep 7, 1985 | 17Florida State 17, 10Nebraska 13upset | Box score |
| Sep 7, 1985 | 16Oklahoma State 31, 12Washington 17upset | Box score |
| Sep 7, 1985 | 20UCLA 27, 8BYU 24upset | Box score |
Upsets
A ranked team beaten as the betting favorite, or, where no line is on file, by an unranked or lower-ranked team.
FBS vs. FBS
| Sep 7, 1985 | Arizona 23, Toledo 10 | Box score |
| Sep 7, 1985 | 2Auburn 49, Louisiana 7 | Box score |
| Sep 7, 1985 | Baylor 39, Wyoming 18 | Box score |
| Sep 7, 1985 | Boston College 28, Temple 25 | Box score |
| Sep 7, 1985 | Bowling Green 31, Ball State 6 | Box score |
| Sep 7, 1985 | Colorado 23, Colorado State 10 | Box score |
| Sep 7, 1985 | Duke 40, Northwestern 17 | Box score |
| Sep 7, 1985 | East Carolina 33, NC State 14 | Box score |
| Sep 7, 1985 | 5Florida 35, Miami 23 | Box score |
| Sep 7, 1985 | 17Florida State 17, 10Nebraska 13upset | Box score |
| Sep 7, 1985 | Memphis 17, Ole Miss 17 | Box score |
| Sep 7, 1985 | North Carolina 21, Navy 19 | Box score |
| Sep 7, 1985 | Northern Illinois 17, Western Michigan 0 | Box score |
| Sep 7, 1985 | 16Oklahoma State 31, 12Washington 17upset | Box score |
| Sep 7, 1985 | 19Penn State 20, 7Maryland 18upset | Box score |
| Sep 7, 1985 | San José State 32, New Mexico State 3 | Box score |
| Sep 7, 1985 | 6USC 20, 11Illinois 10 | Box score |
| Sep 7, 1985 | 3SMU 35, UTEP 23 | Box score |
| Sep 7, 1985 | Texas Tech 32, New Mexico 31 | Box score |
| Sep 7, 1985 | Tulsa 31, Houston 24 | Box score |
| Sep 7, 1985 | 20UCLA 27, 8BYU 24upset | Box score |
| Sep 7, 1985 | Utah State 19, Long Beach State 17upset | Box score |
| Sep 7, 1985 | Washington State 20, California 19 | Box score |
| Sep 7, 1985 | West Virginia 52, Louisville 13 | Box score |
| Sep 7, 1985 | Wichita State 16, Kansas State 10upset | Box score |
Everyone else
| Sep 7, 1985 | Abilene Christian 25, West Texas 18upset | Box score |
| Sep 7, 1985 | Cincinnati 31, Austin Peay 9 | Box score |
| Sep 7, 1985 | Drake 24, Northern Iowa 9 | Box score |
| Sep 7, 1985 | Eastern Michigan 27, Youngstown State 22 | Box score |
| Sep 7, 1985 | Illinois State 18, Western Illinois 6 | Box score |
| Sep 7, 1985 | Indiana State 31, St. Cloud State 14 | Box score |
| Sep 7, 1985 | Mississippi State 22, Arkansas State 14 | Box score |
| Sep 7, 1985 | Missouri State 40, Southern Illinois 28 | Box score |
| Sep 7, 1985 | Montana 31, Cal State Fullerton 30upset | Box score |
| Sep 7, 1985 | UNLV 35, Tennessee Tech 7 | Box score |
| Sep 7, 1985 | Oregon State 43, Idaho 28 | Box score |
| Sep 7, 1985 | Pacific 49, Sacramento State 17 | Box score |
| Sep 7, 1985 | Richmond 24, Virginia Tech 14upset | Box score |
| Sep 7, 1985 | 18South Carolina 20, App State 13 | Box score |
| Sep 7, 1985 | Southern Miss 28, Louisiana Tech 0 | Box score |
| Sep 7, 1985 | Utah 20, Boise State 17 | Box score |
| Sep 7, 1985 | Vanderbilt 7, Chattanooga 0 | Box score |
| Sep 7, 1985 | Wake Forest 30, William & Mary 23 | Box score |