| Oct 13, 1979 | 2Alabama 40, Florida 0 | Box score |
| Oct 13, 1979 | Arizona 24, Oregon 13 | Box score |
| Oct 13, 1979 | Arizona State 12, 6Washington 7upset | Box score |
| Oct 13, 1979 | 12Arkansas 20, Texas Tech 6 | Box score |
| Oct 13, 1979 | Arkansas State 14, Louisiana Tech 7 | Box score |
| Oct 13, 1979 | 18Auburn 52, Vanderbilt 35 | Box score |
| Oct 13, 1979 | Ball State 42, Illinois State 14 | Box score |
| Oct 13, 1979 | Baylor 24, SMU 21 | Box score |
| Oct 13, 1979 | Bowling Green 28, Kent State 17 | Box score |
| Oct 13, 1979 | 16BYU 48, Utah State 24 | Box score |
| Oct 13, 1979 | Brown 24, Pennsylvania 18 | Box score |
| Oct 13, 1979 | California 45, Oregon State 0 | Box score |
| Oct 13, 1979 | Central Michigan 31, Northern Illinois 11 | Box score |
| Oct 13, 1979 | Clemson 21, Virginia Tech 0 | Box score |
| Oct 13, 1979 | Colgate 17, Holy Cross 16upset | Box score |
| Oct 13, 1979 | Colorado State 17, UTEP 3 | Box score |
| Oct 13, 1979 | Cornell 41, Harvard 14 | Box score |
| Oct 13, 1979 | Duke 34, Richmond 7 | Box score |
| Oct 13, 1979 | East Carolina 49, The Citadel 7 | Box score |
| Oct 13, 1979 | 9Florida State 17, Mississippi State 6 | Box score |
| Oct 13, 1979 | Furman 34, Marshall 24 | Box score |
| Oct 13, 1979 | Georgia 21, 13LSU 14upset | Box score |
| Oct 13, 1979 | 7Houston 17, Texas A&M 14 | Box score |
| Oct 13, 1979 | Iowa 58, Northwestern 6 | Box score |
| Oct 13, 1979 | Iowa State 7, Kansas State 3 | Box score |
| Oct 13, 1979 | Kentucky 14, Ole Miss 3 | Box score |
| Oct 13, 1979 | Long Beach State 17, Drake 14 | Box score |
| Oct 13, 1979 | UL Monroe 21, Memphis 20upset | Box score |
| Oct 13, 1979 | Louisville 24, Tulsa 7 | Box score |
| Oct 13, 1979 | McNeese 34, Lamar 25 | Box score |
| Oct 13, 1979 | 11Michigan 31, Minnesota 21 | Box score |
| Oct 13, 1979 | Navy 24, William & Mary 7 | Box score |
| Oct 13, 1979 | 5Nebraska 42, Kansas 0 | Box score |
| Oct 13, 1979 | UNLV 28, New Mexico 20 | Box score |
| Oct 13, 1979 | 17NC State 7, Maryland 0 | Box score |
| Oct 13, 1979 | North Texas 21, New Mexico State 7 | Box score |
| Oct 13, 1979 | 10Notre Dame 38, Air Force 13 | Box score |
| Oct 13, 1979 | Ohio 9, Miami (OH) 7upset | Box score |
| Oct 13, 1979 | 8Ohio State 47, Indiana 6 | Box score |
| Oct 13, 1979 | Oklahoma State 14, 15Missouri 13upset | Box score |
| Oct 13, 1979 | Pacific 10, Louisiana 7 | Box score |
| Oct 13, 1979 | Penn State 24, Army 3 | Box score |
| Oct 13, 1979 | Pittsburgh 35, Cincinnati 0 | Box score |
| Oct 13, 1979 | Princeton 35, Columbia 7 | Box score |
| Oct 13, 1979 | 20Purdue 28, Illinois 14 | Box score |
| Oct 13, 1979 | San Diego State 31, Miami 20 | Box score |
| Oct 13, 1979 | San José State 35, Fresno State 22 | Box score |
| Oct 13, 1979 | Southern Illinois 31, Wichita State 7 | Box score |
| Oct 13, 1979 | 1USC 21, Stanford 21 | Box score |
| Oct 13, 1979 | Temple 49, Syracuse 17 | Box score |
| Oct 13, 1979 | Tennessee 31, Georgia Tech 0 | Box score |
| Oct 13, 1979 | 4Texas 16, 3Oklahoma 7upset | Box score |
| Oct 13, 1979 | TCU 17, Rice 7 | Box score |
| Oct 13, 1979 | Toledo 17, Western Michigan 0 | Box score |
| Oct 13, 1979 | Tulane 20, Southern Miss 19 | Box score |
| Oct 13, 1979 | Utah 24, Wyoming 14 | Box score |
| Oct 13, 1979 | VMI 27, App State 22 | Box score |
| Oct 13, 1979 | Wake Forest 24, 14North Carolina 19upset | Box score |
| Oct 13, 1979 | Washington State 17, UCLA 14upset | Box score |
| Oct 13, 1979 | West Texas 33, Indiana State 17 | Box score |
| Oct 13, 1979 | West Virginia 20, Boston College 18 | Box score |
| Oct 13, 1979 | Wisconsin 38, 19Michigan State 29upset | Box score |
| Oct 13, 1979 | Yale 3, Dartmouth 0 | Box score |