| Oct 29, 1977 | 2Alabama 37, Mississippi State 7 | Box score |
| Oct 29, 1977 | Arizona State 47, Utah 19 | Box score |
| Oct 29, 1977 | 8Arkansas 30, Rice 7 | Box score |
| Oct 29, 1977 | Arkansas State 31, UL Monroe 20 | Box score |
| Oct 29, 1977 | Army 48, Holy Cross 7 | Box score |
| Oct 29, 1977 | Auburn 29, 18Florida 14upset | Box score |
| Oct 29, 1977 | Ball State 38, App State 7 | Box score |
| Oct 29, 1977 | Boston College 36, Air Force 14 | Box score |
| Oct 29, 1977 | 17BYU 34, Arizona 14 | Box score |
| Oct 29, 1977 | Brown 20, Harvard 15 | Box score |
| Oct 29, 1977 | California 17, 10USC 14upset | Box score |
| Oct 29, 1977 | Central Michigan 35, Bowling Green 28 | Box score |
| Oct 29, 1977 | Chattanooga 21, The Citadel 14 | Box score |
| Oct 29, 1977 | 16Clemson 26, Wake Forest 0 | Box score |
| Oct 29, 1977 | Dartmouth 14, Columbia 7 | Box score |
| Oct 29, 1977 | Drake 43, Lamar 21 | Box score |
| Oct 29, 1977 | Duke 25, Georgia Tech 24upset | Box score |
| Oct 29, 1977 | 20Florida State 35, North Texas 14 | Box score |
| Oct 29, 1977 | Georgia 23, Richmond 7 | Box score |
| Oct 29, 1977 | Grambling 28, Texas Southern 14 | Box score |
| Oct 29, 1977 | Houston 42, TCU 14 | Box score |
| Oct 29, 1977 | Indiana 34, 19Minnesota 22upset | Box score |
| Oct 29, 1977 | Iowa State 41, Kansas 3 | Box score |
| Oct 29, 1977 | 7Kentucky 32, Virginia Tech 0 | Box score |
| Oct 29, 1977 | Louisiana 9, East Carolina 7 | Box score |
| Oct 29, 1977 | LSU 28, Ole Miss 21 | Box score |
| Oct 29, 1977 | Louisiana Tech 34, Texas–Arlington 12 | Box score |
| Oct 29, 1977 | Louisville 56, Marshall 0 | Box score |
| Oct 29, 1977 | Memphis 42, Southern Miss 14 | Box score |
| Oct 29, 1977 | Miami (OH) 27, Toledo 3 | Box score |
| Oct 29, 1977 | 6Michigan 23, Iowa 6 | Box score |
| Oct 29, 1977 | Michigan State 49, Illinois 20 | Box score |
| Oct 29, 1977 | Missouri 24, 15Colorado 14upset | Box score |
| Oct 29, 1977 | 12Nebraska 31, Oklahoma State 14 | Box score |
| Oct 29, 1977 | New Mexico 35, New Mexico State 13 | Box score |
| Oct 29, 1977 | North Carolina 16, Maryland 7 | Box score |
| Oct 29, 1977 | NC State 7, South Carolina 3 | Box score |
| Oct 29, 1977 | Northern Illinois 21, Kent State 18upset | Box score |
| Oct 29, 1977 | 5Notre Dame 43, Navy 10 | Box score |
| Oct 29, 1977 | 3Ohio State 42, Wisconsin 0 | Box score |
| Oct 29, 1977 | 4Oklahoma 42, Kansas State 7 | Box score |
| Oct 29, 1977 | Pacific 24, San José State 7upset | Box score |
| Oct 29, 1977 | 9Penn State 49, Miami 7 | Box score |
| Oct 29, 1977 | Pennsylvania 21, Princeton 10 | Box score |
| Oct 29, 1977 | 13Pittsburgh 48, Tulane 0 | Box score |
| Oct 29, 1977 | Purdue 28, Northwestern 16 | Box score |
| Oct 29, 1977 | Rutgers 22, William & Mary 21 | Box score |
| Oct 29, 1977 | San Diego State 41, Tulsa 7 | Box score |
| Oct 29, 1977 | Stanford 26, Oregon State 7 | Box score |
| Oct 29, 1977 | Syracuse 6, Virginia 3 | Box score |
| Oct 29, 1977 | Cincinnati 17, Temple 17 | Box score |
| Oct 29, 1977 | Tennessee State 15, Southern 7upset | Box score |
| Oct 29, 1977 | 1Texas 26, 14Texas Tech 0 | Box score |
| Oct 29, 1977 | 11Texas A&M 38, SMU 21 | Box score |
| Oct 29, 1977 | UCLA 20, Washington 12 | Box score |
| Oct 29, 1977 | Villanova 41, West Virginia 36upset | Box score |
| Oct 29, 1977 | Washington State 56, Oregon 20 | Box score |
| Oct 29, 1977 | West Texas 31, Indiana State 20 | Box score |
| Oct 29, 1977 | Western Michigan 28, Ohio 22 | Box score |
| Oct 29, 1977 | Wichita State 35, Long Beach State 21 | Box score |
| Oct 29, 1977 | Wyoming 29, Colorado State 13 | Box score |
| Oct 29, 1977 | Yale 28, Cornell 0 | Box score |