| Sep 29, 1973 | Air Force 10, New Mexico 6 | Box score |
| Sep 29, 1973 | 5Alabama 44, Vanderbilt 0 | Box score |
| Sep 29, 1973 | App State 24, Davidson 8 | Box score |
| Sep 29, 1973 | 13Arizona State 67, Colorado State 14 | Box score |
| Sep 29, 1973 | Arkansas 21, Iowa State 19 | Box score |
| Sep 29, 1973 | Boston College 32, Texas A&M 24 | Box score |
| Sep 29, 1973 | Bowling Green 31, Western Michigan 20 | Box score |
| Sep 29, 1973 | BYU 37, Oregon State 14 | Box score |
| Sep 29, 1973 | California 51, Army 6 | Box score |
| Sep 29, 1973 | Colorado 52, Baylor 28 | Box score |
| Sep 29, 1973 | Cornell 35, Colgate 21 | Box score |
| Sep 29, 1973 | Drake 24, Lamar 10 | Box score |
| Sep 29, 1973 | East Carolina 14, Furman 3 | Box score |
| Sep 29, 1973 | Georgia 31, 19NC State 12upset | Box score |
| Sep 29, 1973 | Georgia Tech 29, Clemson 21 | Box score |
| Sep 29, 1973 | 15Houston 35, Memphis 21 | Box score |
| Sep 29, 1973 | Indiana 17, Kentucky 3 | Box score |
| Sep 29, 1973 | Kansas 34, Minnesota 19 | Box score |
| Sep 29, 1973 | Kansas State 17, Tampa 0upset | Box score |
| Sep 29, 1973 | North Texas 0, Long Beach State 0 | Box score |
| Sep 29, 1973 | 10LSU 24, Rice 9 | Box score |
| Sep 29, 1973 | Maryland 31, Villanova 3 | Box score |
| Sep 29, 1973 | 18Miami 14, Florida State 10 | Box score |
| Sep 29, 1973 | Miami (OH) 13, South Carolina 11 | Box score |
| Sep 29, 1973 | 4Michigan 14, Navy 0 | Box score |
| Sep 29, 1973 | Ole Miss 41, Southern Miss 0 | Box score |
| Sep 29, 1973 | Mississippi State 33, 16Florida 12upset | Box score |
| Sep 29, 1973 | 20Missouri 27, North Carolina 14 | Box score |
| Sep 29, 1973 | 2Nebraska 20, Wisconsin 16 | Box score |
| Sep 29, 1973 | New Mexico State 44, Wichita State 18 | Box score |
| Sep 29, 1973 | Northern Illinois 21, West Texas 14 | Box score |
| Sep 29, 1973 | 7Notre Dame 20, Purdue 7 | Box score |
| Sep 29, 1973 | 3Ohio State 37, TCU 3 | Box score |
| Sep 29, 1973 | 1USC 7, 8Oklahoma 7 | Box score |
| Sep 29, 1973 | 12Oklahoma State 70, Southern Illinois 7 | Box score |
| Sep 29, 1973 | 6Penn State 27, Iowa 8 | Box score |
| Sep 29, 1973 | Pittsburgh 21, Northwestern 14 | Box score |
| Sep 29, 1973 | Richmond 41, Wake Forest 0 | Box score |
| Sep 29, 1973 | Rutgers 39, Princeton 14 | Box score |
| Sep 29, 1973 | San Diego State 17, Kent State 9 | Box score |
| Sep 29, 1973 | SMU 37, Virginia Tech 6 | Box score |
| Sep 29, 1973 | Stanford 23, San José State 12 | Box score |
| Sep 29, 1973 | Temple 63, Holy Cross 34 | Box score |
| Sep 29, 1973 | 9Tennessee 21, 11Auburn 0 | Box score |
| Sep 29, 1973 | 14Texas 28, Texas Tech 12 | Box score |
| Sep 29, 1973 | Toledo 35, Ohio 8 | Box score |
| Sep 29, 1973 | Tulane 42, VMI 0 | Box score |
| Sep 29, 1973 | Tulsa 16, Cincinnati 13 | Box score |
| Sep 29, 1973 | 17UCLA 34, Michigan State 21 | Box score |
| Sep 29, 1973 | Utah 35, Oregon 17 | Box score |
| Sep 29, 1973 | Virginia 7, Duke 3 | Box score |
| Sep 29, 1973 | Washington 21, Syracuse 7 | Box score |
| Sep 29, 1973 | Washington State 51, Idaho 24 | Box score |
| Sep 29, 1973 | West Virginia 17, Illinois 10 | Box score |
| Sep 29, 1973 | William & Mary 24, The Citadel 12 | Box score |
| Sep 29, 1973 | Wyoming 31, UTEP 8 | Box score |
| Sep 29, 1973 | Xavier 30, Marshall 28upset | Box score |