| Sep 25, 1971 | Air Force 23, Wyoming 19 | Box score |
| Sep 25, 1971 | 8Alabama 38, Florida 0 | Box score |
| Sep 25, 1971 | Arizona 14, UTEP 6 | Box score |
| Sep 25, 1971 | 15Arizona State 41, Utah 21 | Box score |
| Sep 25, 1971 | Army 16, Georgia Tech 13upset | Box score |
| Sep 25, 1971 | 5Auburn 10, 9Tennessee 9 | Box score |
| Sep 25, 1971 | Baylor 10, Indiana 0 | Box score |
| Sep 25, 1971 | Boston College 49, Navy 6 | Box score |
| Sep 25, 1971 | Bowling Green 47, East Carolina 21 | Box score |
| Sep 25, 1971 | California 34, San José State 10 | Box score |
| Sep 25, 1971 | 10Colorado 20, 6Ohio State 14upset | Box score |
| Sep 25, 1971 | Cornell 38, Colgate 20 | Box score |
| Sep 25, 1971 | Drake 10, Louisville 7 | Box score |
| Sep 25, 1971 | 20Duke 28, Virginia 0 | Box score |
| Sep 25, 1971 | Florida State 30, Kansas 7 | Box score |
| Sep 25, 1971 | 14Georgia 28, Clemson 0 | Box score |
| Sep 25, 1971 | Holy Cross 21, Harvard 16upset | Box score |
| Sep 25, 1971 | Houston 12, Cincinnati 3 | Box score |
| Sep 25, 1971 | Idaho 10, Colorado State 0 | Box score |
| Sep 25, 1971 | Iowa State 44, New Mexico 20 | Box score |
| Sep 25, 1971 | Kansas State 23, BYU 7 | Box score |
| Sep 25, 1971 | Long Beach State 15, Pacific 14 | Box score |
| Sep 25, 1971 | 18LSU 38, Wisconsin 28 | Box score |
| Sep 25, 1971 | Marshall 15, Xavier 13 | Box score |
| Sep 25, 1971 | Miami 29, Wake Forest 10upset | Box score |
| Sep 25, 1971 | Miami (OH) 14, Dayton 0 | Box score |
| Sep 25, 1971 | 4Michigan 38, UCLA 0 | Box score |
| Sep 25, 1971 | Michigan State 31, Oregon State 14 | Box score |
| Sep 25, 1971 | Ole Miss 34, Kentucky 20 | Box score |
| Sep 25, 1971 | Missouri 24, SMU 12 | Box score |
| Sep 25, 1971 | 1Nebraska 34, Texas A&M 7 | Box score |
| Sep 25, 1971 | New Mexico State 10, North Texas 0 | Box score |
| Sep 25, 1971 | North Carolina 35, Maryland 14 | Box score |
| Sep 25, 1971 | Northwestern 12, Syracuse 6 | Box score |
| Sep 25, 1971 | 2Notre Dame 8, Purdue 7 | Box score |
| Sep 25, 1971 | Ohio 37, Kent State 21 | Box score |
| Sep 25, 1971 | 11Oklahoma 55, Pittsburgh 29 | Box score |
| Sep 25, 1971 | Oklahoma State 24, Virginia Tech 16 | Box score |
| Sep 25, 1971 | 12Penn State 44, Iowa 14 | Box score |
| Sep 25, 1971 | Rice 14, Tulane 11 | Box score |
| Sep 25, 1971 | Rutgers 33, Princeton 18upset | Box score |
| Sep 25, 1971 | South Carolina 24, NC State 6 | Box score |
| Sep 25, 1971 | 16USC 28, Illinois 0 | Box score |
| Sep 25, 1971 | Southern Miss 10, San Diego State 0 | Box score |
| Sep 25, 1971 | 13Stanford 38, Oregon 17 | Box score |
| Sep 25, 1971 | 3Texas 28, Texas Tech 0 | Box score |
| Sep 25, 1971 | 19Toledo 23, Texas–Arlington 0 | Box score |
| Sep 25, 1971 | Tulsa 21, 7Arkansas 20upset | Box score |
| Sep 25, 1971 | Vanderbilt 49, Mississippi State 19 | Box score |
| Sep 25, 1971 | Villanova 13, VMI 3 | Box score |
| Sep 25, 1971 | 17Washington 44, TCU 26 | Box score |
| Sep 25, 1971 | Washington State 31, Minnesota 20upset | Box score |
| Sep 25, 1971 | West Virginia 16, Richmond 3 | Box score |
| Sep 25, 1971 | Western Michigan 27, Northern Illinois 17 | Box score |
| Sep 25, 1971 | William & Mary 40, Davidson 14 | Box score |