| Sep 26, 1970 | 20Air Force 37, 9Missouri 14upset | Box score |
| Sep 26, 1970 | Alabama 46, 13Florida 15upset | Box score |
| Sep 26, 1970 | Arizona 30, San José State 29 | Box score |
| Sep 26, 1970 | Arizona State 35, Kansas State 13 | Box score |
| Sep 26, 1970 | 12Arkansas 49, Tulsa 7 | Box score |
| Sep 26, 1970 | Auburn 36, 17Tennessee 23upset | Box score |
| Sep 26, 1970 | Boston College 28, Navy 14 | Box score |
| Sep 26, 1970 | California 56, Indiana 14 | Box score |
| Sep 26, 1970 | Cincinnati 17, William & Mary 10 | Box score |
| Sep 26, 1970 | The Citadel 31, East Carolina 0 | Box score |
| Sep 26, 1970 | 18Colorado 41, 4Penn State 13upset | Box score |
| Sep 26, 1970 | Cornell 17, Colgate 7 | Box score |
| Sep 26, 1970 | Davidson 14, Richmond 5upset | Box score |
| Sep 26, 1970 | Bowling Green 14, Dayton 14 | Box score |
| Sep 26, 1970 | Duke 17, Virginia 7 | Box score |
| Sep 26, 1970 | Florida State 19, Wake Forest 14 | Box score |
| Sep 26, 1970 | Georgia 38, Clemson 0 | Box score |
| Sep 26, 1970 | 19Georgia Tech 31, Miami 21 | Box score |
| Sep 26, 1970 | Iowa State 37, Colorado State 6 | Box score |
| Sep 26, 1970 | Kansas 31, Syracuse 14upset | Box score |
| Sep 26, 1970 | Kent State 27, Buffalo 21 | Box score |
| Sep 26, 1970 | LSU 24, Rice 0 | Box score |
| Sep 26, 1970 | Louisville 13, North Texas 2 | Box score |
| Sep 26, 1970 | Memphis 21, Virginia Tech 20 | Box score |
| Sep 26, 1970 | Miami (OH) 23, Western Michigan 12 | Box score |
| Sep 26, 1970 | 10Michigan 17, Washington 3 | Box score |
| Sep 26, 1970 | Michigan State 28, Washington State 14 | Box score |
| Sep 26, 1970 | Minnesota 49, Ohio 7 | Box score |
| Sep 26, 1970 | 5Ole Miss 20, Kentucky 17 | Box score |
| Sep 26, 1970 | Mississippi State 20, Vanderbilt 6upset | Box score |
| Sep 26, 1970 | 8Nebraska 28, Army 0 | Box score |
| Sep 26, 1970 | New Mexico 34, Utah 28upset | Box score |
| Sep 26, 1970 | North Carolina 53, Maryland 20 | Box score |
| Sep 26, 1970 | Northern Illinois 18, Xavier 0upset | Box score |
| Sep 26, 1970 | 6Notre Dame 48, Purdue 0 | Box score |
| Sep 26, 1970 | 1Ohio State 56, Texas A&M 13 | Box score |
| Sep 26, 1970 | Oklahoma State 26, 11Houston 17upset | Box score |
| Sep 26, 1970 | Oregon State 23, 14Oklahoma 14upset | Box score |
| Sep 26, 1970 | Pacific 17, Idaho 10 | Box score |
| Sep 26, 1970 | Pittsburgh 15, Baylor 10 | Box score |
| Sep 26, 1970 | Princeton 41, Rutgers 14 | Box score |
| Sep 26, 1970 | San Diego State 35, Cal State Los Angeles 0 | Box score |
| Sep 26, 1970 | NC State 7, South Carolina 7 | Box score |
| Sep 26, 1970 | 7USC 48, Iowa 0 | Box score |
| Sep 26, 1970 | SMU 34, New Mexico State 21 | Box score |
| Sep 26, 1970 | 3Stanford 33, Oregon 10 | Box score |
| Sep 26, 1970 | 2Texas 35, Texas Tech 13 | Box score |
| Sep 26, 1970 | Wisconsin 14, TCU 14 | Box score |
| Sep 26, 1970 | UTEP 17, BYU 0upset | Box score |
| Sep 26, 1970 | Toledo 52, Marshall 3 | Box score |
| Sep 26, 1970 | Tulane 23, Illinois 9 | Box score |
| Sep 26, 1970 | 15UCLA 12, Northwestern 7 | Box score |
| Sep 26, 1970 | Utah State 42, Wyoming 29 | Box score |
| Sep 26, 1970 | West Texas 43, Wichita State 0 | Box score |
| Sep 26, 1970 | 16West Virginia 47, VMI 10 | Box score |