| Sep 18, 1970 | Miami 36, William & Mary 14 | Box score |
| Sep 19, 1970 | Air Force 41, Wyoming 17 | Box score |
| Sep 19, 1970 | Alabama 51, Virginia Tech 18 | Box score |
| Sep 19, 1970 | 20Arizona State 38, Colorado State 9 | Box score |
| Sep 19, 1970 | 11Arkansas 23, Oklahoma State 7 | Box score |
| Sep 19, 1970 | Arkansas State 53, Wichita State 14 | Box score |
| Sep 19, 1970 | Auburn 33, Southern Miss 14 | Box score |
| Sep 19, 1970 | Baylor 10, Army 7upset | Box score |
| Sep 19, 1970 | Boston College 28, Villanova 21 | Box score |
| Sep 19, 1970 | Cincinnati 13, Dayton 7 | Box score |
| Sep 19, 1970 | Clemson 27, Virginia 17 | Box score |
| Sep 19, 1970 | Colorado 16, Indiana 9 | Box score |
| Sep 19, 1970 | Duke 13, Maryland 12 | Box score |
| Sep 19, 1970 | 14Florida 34, Mississippi State 13 | Box score |
| Sep 19, 1970 | Georgia Tech 23, Florida State 13 | Box score |
| Sep 19, 1970 | 15Houston 42, Syracuse 15 | Box score |
| Sep 19, 1970 | Illinois 20, Oregon 16upset | Box score |
| Sep 19, 1970 | Iowa State 32, New Mexico 3 | Box score |
| Sep 19, 1970 | Kentucky 16, 13Kansas State 3upset | Box score |
| Sep 19, 1970 | Miami (OH) 28, Xavier 7 | Box score |
| Sep 19, 1970 | 8Michigan 20, Arizona 9 | Box score |
| Sep 19, 1970 | 5Ole Miss 47, Memphis 13 | Box score |
| Sep 19, 1970 | 10Missouri 34, Minnesota 12 | Box score |
| Sep 19, 1970 | 3USC 21, 9Nebraska 21 | Box score |
| Sep 19, 1970 | North Carolina 19, NC State 0 | Box score |
| Sep 19, 1970 | 6Notre Dame 35, Northwestern 14 | Box score |
| Sep 19, 1970 | Ohio 24, Kent State 14 | Box score |
| Sep 19, 1970 | 18Oklahoma 21, Wisconsin 7 | Box score |
| Sep 19, 1970 | Oregon State 21, Iowa 14 | Box score |
| Sep 19, 1970 | Pacific 9, Long Beach State 6 | Box score |
| Sep 19, 1970 | 7Penn State 55, Navy 7 | Box score |
| Sep 19, 1970 | Purdue 15, TCU 0 | Box score |
| Sep 19, 1970 | Rice 42, VMI 0 | Box score |
| Sep 19, 1970 | San Diego State 23, North Texas 0 | Box score |
| Sep 19, 1970 | South Carolina 43, Wake Forest 7 | Box score |
| Sep 19, 1970 | 4Stanford 34, San José State 3 | Box score |
| Sep 19, 1970 | Tennessee 28, SMU 3 | Box score |
| Sep 19, 1970 | 2Texas 56, California 15 | Box score |
| Sep 19, 1970 | Texas A&M 20, 12LSU 18upset | Box score |
| Sep 19, 1970 | Texas Tech 23, Kansas 0 | Box score |
| Sep 19, 1970 | Toledo 27, Buffalo 6 | Box score |
| Sep 19, 1970 | Tulane 17, 19Georgia 14upset | Box score |
| Sep 19, 1970 | 16UCLA 24, Pittsburgh 15 | Box score |
| Sep 19, 1970 | Utah 44, UTEP 20 | Box score |
| Sep 19, 1970 | Utah State 33, Bowling Green 14 | Box score |
| Sep 19, 1970 | Vanderbilt 52, The Citadel 0 | Box score |
| Sep 19, 1970 | Washington 42, Michigan State 16 | Box score |
| Sep 19, 1970 | Washington State 44, Idaho 16 | Box score |
| Sep 19, 1970 | 17West Virginia 49, Richmond 10 | Box score |
| Sep 19, 1970 | Western Michigan 35, BYU 17 | Box score |