| Sep 17, 1966 | Arizona State 30, UTEP 26 | Box score |
| Sep 17, 1966 | 5Arkansas 14, Oklahoma State 10 | Box score |
| Sep 17, 1966 | Army 21, Kansas State 6 | Box score |
| Sep 17, 1966 | Buffalo 27, Kent State 23 | Box score |
| Sep 17, 1966 | California 21, Washington State 6 | Box score |
| Sep 17, 1966 | Dayton 23, Richmond 0 | Box score |
| Sep 17, 1966 | Duke 34, West Virginia 15 | Box score |
| Sep 17, 1966 | William & Mary 7, East Carolina 7 | Box score |
| Sep 17, 1966 | Florida 43, Northwestern 7 | Box score |
| Sep 17, 1966 | Georgia 20, Mississippi State 17 | Box score |
| Sep 17, 1966 | Georgia Tech 38, Texas A&M 3 | Box score |
| Sep 17, 1966 | Houston 21, Florida State 13upset | Box score |
| Sep 17, 1966 | Iowa 31, Arizona 20 | Box score |
| Sep 17, 1966 | Kentucky 10, North Carolina 0 | Box score |
| Sep 17, 1966 | LSU 28, South Carolina 12 | Box score |
| Sep 17, 1966 | Miami 24, Colorado 3 | Box score |
| Sep 17, 1966 | Miami (OH) 20, Indiana 10 | Box score |
| Sep 17, 1966 | Michigan 41, Oregon State 0 | Box score |
| Sep 17, 1966 | 2Michigan State 28, NC State 10 | Box score |
| Sep 17, 1966 | Ole Miss 13, Memphis 0 | Box score |
| Sep 17, 1966 | Missouri 24, Minnesota 0 | Box score |
| Sep 17, 1966 | Navy 27, Boston College 7 | Box score |
| Sep 17, 1966 | 3Nebraska 14, TCU 10 | Box score |
| Sep 17, 1966 | New Mexico 17, Utah State 8 | Box score |
| Sep 17, 1966 | North Texas 25, New Mexico State 21 | Box score |
| Sep 17, 1966 | Oklahoma 17, Oregon 0 | Box score |
| Sep 17, 1966 | Penn State 15, Maryland 7 | Box score |
| Sep 17, 1966 | 8Purdue 42, Ohio 3 | Box score |
| Sep 17, 1966 | 9USC 10, Texas 6 | Box score |
| Sep 17, 1966 | SMU 26, Illinois 7 | Box score |
| Sep 17, 1966 | Stanford 25, San José State 21 | Box score |
| Sep 17, 1966 | Texas Tech 23, Kansas 7 | Box score |
| Sep 17, 1966 | Toledo 9, Xavier 0 | Box score |
| Sep 17, 1966 | Tulane 13, Virginia Tech 0 | Box score |
| Sep 17, 1966 | Tulsa 57, Tampa 11 | Box score |
| Sep 17, 1966 | 4UCLA 57, Pittsburgh 14 | Box score |
| Sep 17, 1966 | Vanderbilt 24, The Citadel 0 | Box score |
| Sep 17, 1966 | Virginia 24, Wake Forest 10 | Box score |
| Sep 17, 1966 | VMI 14, Villanova 13 | Box score |
| Sep 17, 1966 | Washington 19, Idaho 7 | Box score |
| Sep 17, 1966 | Wisconsin 20, Iowa State 10 | Box score |
| Sep 17, 1966 | Wyoming 13, Air Force 0 | Box score |