1960: Week 2
41 games. Five ranked teams lost, all to unranked teams. Winners are listed first; numbers before names are AP ranks going in.
The week in review
Upsets
| Sep 17, 1960 | Nebraska 14, 4Texas 13upset | Box score |
| Sep 16, 1960 | Oregon State 14, 6USC 0upset | Box score |
| Sep 17, 1960 | UCLA 8, 7Pittsburgh 7upset | Box score |
| Sep 17, 1960 | Kansas 21, 11TCU 7upset | Box score |
| Sep 17, 1960 | Alabama 21, 13Georgia 6upset | Box score |
A ranked team beaten as the betting favorite, or, where no line is on file, by an unranked or lower-ranked team.
FBS vs. FBS
| Sep 16, 1960 | Oregon State 14, 6USC 0upset | Box score |
| Sep 17, 1960 | Alabama 21, 13Georgia 6upset | Box score |
| Sep 17, 1960 | Arizona State 39, Colorado State 0 | Box score |
| Sep 17, 1960 | 19Arkansas 9, Oklahoma State 0 | Box score |
| Sep 17, 1960 | Army 37, Buffalo 0 | Box score |
| Sep 17, 1960 | Cincinnati 15, Hardin Simmons 14 | Box score |
| Sep 17, 1960 | Denver 28, Wichita State 19upset | Box score |
| Sep 17, 1960 | Florida 30, George Washington 7 | Box score |
| Sep 17, 1960 | Florida State 28, Richmond 0 | Box score |
| Sep 17, 1960 | Georgia Tech 23, Kentucky 13 | Box score |
| Sep 17, 1960 | Iowa State 46, Drake 0 | Box score |
| Sep 17, 1960 | Kansas 21, 11TCU 7upset | Box score |
| Sep 17, 1960 | LSU 9, Texas A&M 0 | Box score |
| Sep 17, 1960 | Marquette 23, Villanova 13 | Box score |
| Sep 17, 1960 | Maryland 31, West Virginia 8 | Box score |
| Sep 17, 1960 | 2Ole Miss 42, Houston 0 | Box score |
| Sep 17, 1960 | Missouri 20, SMU 0 | Box score |
| Sep 17, 1960 | Navy 22, Boston College 7 | Box score |
| Sep 17, 1960 | Nebraska 14, 4Texas 13upset | Box score |
| Sep 17, 1960 | New Mexico State 38, Tulsa 18 | Box score |
| Sep 17, 1960 | NC State 29, Virginia Tech 14 | Box score |
| Sep 17, 1960 | Ohio 28, Dayton 0 | Box score |
| Sep 17, 1960 | Oregon 33, Idaho 6 | Box score |
| Sep 17, 1960 | 19Penn State 20, Boston University 0 | Box score |
| Sep 17, 1960 | Texas Tech 38, West Texas 14 | Box score |
| Sep 17, 1960 | Tulane 7, California 3 | Box score |
| Sep 17, 1960 | UCLA 8, 7Pittsburgh 7upset | Box score |
| Sep 17, 1960 | Utah State 20, UTEP 7 | Box score |
| Sep 17, 1960 | VMI 33, William & Mary 21 | Box score |
| Sep 17, 1960 | 3Washington 55, Pacific 6 | Box score |
| Sep 17, 1960 | Washington State 15, Stanford 14 | Box score |
| Sep 17, 1960 | Wyoming 14, Montana 0 | Box score |
| Sep 17, 1960 | Xavier 17, Miami (OH) 6 | Box score |
Everyone else
| Sep 16, 1960 | BYU 34, Cal Poly 14 | Box score |
| Sep 17, 1960 | The Citadel 19, Newberry 0 | Box score |
| Sep 17, 1960 | Davidson 16, Catawba 7 | Box score |
| Sep 17, 1960 | Furman 20, Presbyterian 12 | Box score |
| Sep 17, 1960 | Kansas State 20, South Dakota State 6 | Box score |
| Sep 17, 1960 | Memphis 35, Texas–Arlington 0 | Box score |
| Sep 17, 1960 | New Mexico 77, University of Mexico 6 | Box score |
| Sep 17, 1960 | Utah 33, Hawai’i 6 | Box score |