| Oct 29, 1948 | 13Clemson 26, Boston College 19 | Box score |
| Oct 29, 1948 | Maryland 27, Miami 13 | Box score |
| Oct 29, 1948 | Vanderbilt 47, Auburn 0 | Box score |
| Oct 29, 1948 | Villanova 27, Detroit Mercy 6 | Box score |
| Oct 30, 1948 | Arizona 33, Arizona State 21 | Box score |
| Oct 30, 1948 | Arkansas 28, Texas A&M 6 | Box score |
| Oct 30, 1948 | 5Army 49, Virginia Tech 7 | Box score |
| Oct 30, 1948 | 20Baylor 6, TCU 3 | Box score |
| Oct 30, 1948 | Boston University 12, Syracuse 7 | Box score |
| Oct 30, 1948 | BYU 26, Montana 20 | Box score |
| Oct 30, 1948 | Brown 20, Rutgers 6upset | Box score |
| Oct 30, 1948 | 4California 13, USC 7 | Box score |
| Oct 30, 1948 | Cornell 20, Columbia 13 | Box score |
| Oct 30, 1948 | Dartmouth 41, Yale 14 | Box score |
| Oct 30, 1948 | Denver 10, Georgetown 10 | Box score |
| Oct 30, 1948 | Florida 39, Furman 14 | Box score |
| Oct 30, 1948 | 18Georgia 35, Alabama 0 | Box score |
| Oct 30, 1948 | 6Georgia Tech 19, Duke 7 | Box score |
| Oct 30, 1948 | UTEP 27, Hardin Simmons 27 | Box score |
| Oct 30, 1948 | Harvard 20, Holy Cross 13 | Box score |
| Oct 30, 1948 | Iowa 19, Wisconsin 13 | Box score |
| Oct 30, 1948 | Kansas 13, Oklahoma State 7 | Box score |
| Oct 30, 1948 | Kentucky 28, Cincinnati 7 | Box score |
| Oct 30, 1948 | Lafayette 33, George Washington 14 | Box score |
| Oct 30, 1948 | 1Michigan 28, Illinois 20 | Box score |
| Oct 30, 1948 | 17Michigan State 46, Oregon State 21 | Box score |
| Oct 30, 1948 | 15Minnesota 30, Indiana 7 | Box score |
| Oct 30, 1948 | Ole Miss 49, LSU 19 | Box score |
| Oct 30, 1948 | 8Missouri 49, Kansas State 7 | Box score |
| Oct 30, 1948 | 3North Carolina 14, Tennessee 7 | Box score |
| Oct 30, 1948 | 9Northwestern 21, Ohio State 7 | Box score |
| Oct 30, 1948 | 2Notre Dame 41, Navy 7 | Box score |
| Oct 30, 1948 | Ohio 14, Duquesne 13 | Box score |
| Oct 30, 1948 | 16Oklahoma 33, Iowa State 6 | Box score |
| Oct 30, 1948 | 14Oregon 14, Saint Mary’s (CA) 13 | Box score |
| Oct 30, 1948 | 12Penn State 32, Colgate 13 | Box score |
| Oct 30, 1948 | 7Pennsylvania 40, Washington and Lee 7 | Box score |
| Oct 30, 1948 | Princeton 55, Virginia 14 | Box score |
| Oct 30, 1948 | Purdue 14, Marquette 9 | Box score |
| Oct 30, 1948 | Rice 14, Texas Tech 7upset | Box score |
| Oct 30, 1948 | 11SMU 21, 20Texas 6 | Box score |
| Oct 30, 1948 | Stanford 20, Washington 0 | Box score |
| Oct 30, 1948 | 19Tulane 9, Mississippi State 0 | Box score |
| Oct 30, 1948 | Wichita State 14, Tulsa 14 | Box score |
| Oct 30, 1948 | UCLA 27, Nebraska 15 | Box score |
| Oct 30, 1948 | Utah 14, Colorado 12 | Box score |
| Oct 30, 1948 | Utah State 45, Wyoming 34 | Box score |
| Oct 30, 1948 | VMI 33, Davidson 6 | Box score |
| Oct 30, 1948 | Wake Forest 34, NC State 13 | Box score |
| Oct 30, 1948 | Washington State 19, Idaho 14 | Box score |
| Oct 30, 1948 | West Virginia 35, South Carolina 12 | Box score |
| Oct 30, 1948 | William & Mary 14, Richmond 6 | Box score |
| Oct 31, 1948 | Santa Clara 25, San Francisco 13 | Box score |