| Sep 23, 1938 | Auburn 14, Birmingham-Southern 0 | Box score |
| Sep 23, 1938 | Bucknell 28, Furman 6 | Box score |
| Sep 23, 1938 | Duquesne 34, Waynesburg 7 | Box score |
| Sep 23, 1938 | Gonzaga 38, Puget Sound 0 | Box score |
| Sep 23, 1938 | New Mexico 40, Western New Mexico 0 | Box score |
| Sep 23, 1938 | New Mexico State 27, Montana State 7 | Box score |
| Sep 23, 1938 | San Francisco 20, Hardin Simmons 0 | Box score |
| Sep 24, 1938 | Army 32, Wichita State 0 | Box score |
| Sep 24, 1938 | Baylor 33, Southwestern U 0 | Box score |
| Sep 24, 1938 | Boston College 63, Canisius 12 | Box score |
| Sep 24, 1938 | Bradley 6, Saint Louis 0upset | Box score |
| Sep 24, 1938 | BYU 19, Northern Arizona 0 | Box score |
| Sep 24, 1938 | Colorado State 12, Colorado School of Mines 6 | Box score |
| Sep 24, 1938 | Dartmouth 46, Bates 0 | Box score |
| Sep 24, 1938 | Drake 47, Monmouth 0 | Box score |
| Sep 24, 1938 | Holy Cross 28, Providence 0 | Box score |
| Sep 24, 1938 | Kentucky 46, Maryville (TN) 7 | Box score |
| Sep 24, 1938 | Loyola Marymount 51, California Tech 0 | Box score |
| Sep 24, 1938 | Michigan State 34, Wayne State 6 | Box score |
| Sep 24, 1938 | Montana 27, Eastern Washington 0 | Box score |
| Sep 24, 1938 | Ohio 6, Illinois 0upset | Box score |
| Sep 24, 1938 | Richmond 19, Maryland 6upset | Box score |
| Sep 24, 1938 | South Carolina 6, Xavier 0 | Box score |
| Sep 24, 1938 | SMU 34, North Texas 7 | Box score |
| Sep 24, 1938 | St. Bonaventure 7, Manhattan 6upset | Box score |
| Sep 24, 1938 | Stetson 16, Florida 14upset | Box score |
| Sep 24, 1938 | Temple 6, Albright 0 | Box score |
| Sep 24, 1938 | Texas A&M 52, Texas A&M–Kingsville 0 | Box score |
| Sep 24, 1938 | Tulsa 20, Central Oklahoma 0 | Box score |
| Sep 24, 1938 | Virginia 12, VMI 12 | Box score |
| Sep 24, 1938 | Washburn 34, Baker 0 | Box score |
| Sep 25, 1938 | Mississippi State 19, Samford 0 | Box score |