1918: Week 1
Seven games. Winners are listed first; numbers before names are AP ranks going in.
FBS vs. FBS
| Sep 28, 1918 | Great Lakes Navy 10, Iowa 0upset | Box score |
| Sep 28, 1918 | Texas 19, TCU 0 | Box score |
Everyone else
| Sep 27, 1918 | Clemson 65, Camp Sevier 0 | Box score |
| Sep 27, 1918 | Kansas State 22, Baker 0 | Box score |
| Sep 28, 1918 | Camp Pike 6, Arkansas 0upset | Box score |
| Sep 28, 1918 | Notre Dame 26, Case 6 | Box score |
| Sep 28, 1918 | Rutgers 66, Ursinus 0 | Box score |